L1CAM Mouse Monoclonal Antibody [Clone ID: UMAB47]
L1CAM mouse monoclonal antibody, clone UMAB47
Product Datasheet for 'UM570043'
|Applications||10k-ChIP, IF, IHC, WB|
|Recommend Dilution||IHC 1:100|
|Immunogen||Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Concentration||0.5~1.0 mg/ml (Lot Dependent)|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||137.8 kDa|
|Gene Name||Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.|
|Background||The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008]|
|Synonyms||CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Transmembrane|
|Protein Pathways||Axon guidance, Cell adhesion molecules (CAMs)|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.