CD5 Mouse Monoclonal Antibody [Clone ID: UMAB9]

CAT#: UM500009

Reviews ()
Write a review

CD5 mouse monoclonal antibody, clone UMAB9

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free



  View other "UMAB9" antibodies (2)

USD 564.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Recombinant protein of human CD5 molecule (CD5)
    • 100 ug

USD 2,950.00


Transient overexpression lysate of CD5 molecule (CD5)
    • 100 ug

USD 436.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00

Specifications

Product Data
Clone Name UMAB9
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:500, IHC 1:100, IF 1:100, FLOW 1:100, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD5 (NP_055022) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 54.4 kDa
Gene Name Homo sapiens CD5 molecule (CD5), transcript variant 1, mRNA.
Background CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of theirB-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 is a good immunohistochemical marker for T-cells. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukaemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukaemia, while relatively rare, is associated with a poor prognosis.
Synonyms LEU1; T1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage

Other Versions

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.