Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: UMAB1]

CAT#: UM500001

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KRT8/CK8 mouse monoclonal antibody, clone UMAB1

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free



USD 564.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
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Specifications

Product Data
Clone Name UMAB1
Applications 10k-ChIP, IF, IHC, WB
Recommended Dilution WB 1:500~1000, IHC 1:50, IF 1:50~100
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 53.5 kDa
Gene Name Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.
Background Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Reference Data
Protein Families Druggable Genome
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