NEDD4 Mouse Monoclonal Antibody [Clone ID: OTI5A8]
USD 867.00
USD 665.00
Specifications
Product Data | |
Clone Name | OTI5A8 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 160-460 of human NEDD4 (NP_940682) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 140.7 kDa |
Gene Name | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
Database Link | |
Background | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016] |
Synonyms | NEDD4-1; RPF1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Endocytosis, Ubiquitin mediated proteolysis |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF812642 | Carrier-free (BSA/glycerol-free) NEDD4 mouse monoclonal antibody,clone OTI5A8 |
USD 600.00 |
|
TA812642 | NEDD4 mouse monoclonal antibody,clone OTI5A8 |
USD 447.00 |
|
TA812642AM | NEDD4 mouse monoclonal antibody,clone OTI5A8, Biotinylated |
USD 509.00 |
|
TA812642BM | NEDD4 mouse monoclonal antibody,clone OTI5A8, HRP conjugated |
USD 509.00 |
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