RNF20 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B9]
CAT#: TA807610AM
RNF20 mouse monoclonal antibody,clone OTI2B9, Biotinylated
Conjugation: Unconjugated HRP
Specifications
Product Data | |
Clone Name | OTI2B9 |
Applications | IHC, WB |
Recommended Dilution | WB 1:500, IHC 1:150 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 493-754 of human RNF20 (NP_062538) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 113.5 kDa |
Gene Name | ring finger protein 20 |
Database Link | |
Background | The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012] |
Synonyms | BRE1; BRE1A; hBRE1 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF807610 | Carrier-free (BSA/glycerol-free) RNF20 mouse monoclonal antibody,clone OTI2B9 |
USD 600.00 |
|
TA807610 | RNF20 mouse monoclonal antibody,clone OTI2B9 |
USD 447.00 |
|
TA807610BM | RNF20 mouse monoclonal antibody,clone OTI2B9, HRP conjugated |
USD 509.00 |
|
TA807610S | RNF20 mouse monoclonal antibody,clone OTI2B9 |
USD 200.00 |
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