PDX1 Mouse Monoclonal Antibody [Clone ID: OTI2A12]
CAT#: TA500038
Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12)
Size: 30 ul
Formulation: Carrier-Free
USD 436.00
Specifications
Product Data | |
Clone Name | OTI2A12 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:20000, IHC 1:50, IF 1:50~100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 30.6 kDa |
Gene Name | pancreatic and duodenal homeobox 1 |
Database Link | |
Background | Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Synonyms | GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1 |
Reference Data | |
Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
Protein Pathways | Maturity onset diabetes of the young, Type II diabetes mellitus |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500038 | Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) |
USD 600.00 |
|
TA500038AM | Pdx1 mouse monoclonal antibody, clone 2A12, Biotinylated |
USD 509.00 |
|
TA500038BM | Pdx1 mouse monoclonal antibody, clone 2A12, HRP conjugated |
USD 509.00 |
|
TA500038S | Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) |
USD 200.00 |
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