PDX1 Mouse Monoclonal Antibody [Clone ID: OTI2A12]

CAT#: TA500038

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Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



  View other "OTI2A12" antibodies (4)

USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Recombinant protein of human pancreatic and duodenal homeobox 1 (PDX1)
    • 100 ug

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Transient overexpression lysate of pancreatic and duodenal homeobox 1 (PDX1)
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

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Specifications

Product Data
Clone Name OTI2A12
Applications IF, IHC, WB
Recommended Dilution WB 1:20000, IHC 1:50, IF 1:50~100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30.6 kDa
Gene Name pancreatic and duodenal homeobox 1
Background Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Synonyms GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Reference Data
Protein Families Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Protein Pathways Maturity onset diabetes of the young, Type II diabetes mellitus

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