AKT3 Mouse Monoclonal Antibody [Clone ID: OTI9B2]

CAT#: TA500001

AKT3 mouse monoclonal antibody, clone OTI9B2 (formerly 9B2)

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 Product Datasheet for 'TA500001'

USD 379


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI9B2
Applications WB, IHC, IF, FC
Recommend Dilution WB 1:500, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human AKT3 (NP_005456) produced in E.coli.
Isotype IgG3
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.25 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 55.6 kDa
Gene Name AKT serine/threonine kinase 3
Background The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
Synonyms MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2
Reference Data
Protein Families Protein Kinase, ES Cell Differentiation/IPS, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Chemokine signaling pathway, mTOR signaling pathway, Apoptosis, VEGF signaling pathway, Focal adhesion, Tight junction, Toll-like receptor signaling pathway, Jak-STAT signaling pathway, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Neurotrophin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Adipocytokine signaling pathway, Pathways in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations