Nociceptin (PNOC) Rabbit Polyclonal Antibody

CAT#: TA364166

Rabbit polyclonal anti Nociceptin; neat antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Nociceptin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg- Lys-Leu-Ala-Asn-Gln-OH coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: prepronociceptin
• Database Link:
  Entrez Gene 5368 Human
  UniProt ID Q13519
• Background: Nociceptin is a 17-amino acid neuropeptide and is the endogenous ligand for the nociceptin receptor (NOP, ORL-1). It initiates its function to act on numerous brain activities such as pain sensation and fear learning. Nociceptin derives from the prepronociceptin protein, as are a further 2 peptides, nocistatin and Noc-II, which inhibit the N/OFQ receptor function. Nociceptin itself acts as a potent anti-analgesic, effectively counteracting the effect of pain-relievers. This antibody was generated by immunization of rabbits with Nociceptin coupled to a carrier protein.
• Synonyms: nocistatin; OFQ; P; PPNOC; prepronociceptin; propronociceptin