CD51 (ITGAV) Rabbit Polyclonal Antibody

CAT#: TA347895

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Rabbit Polyclonal Anti-Integrin aV Antibody


Product Datasheet for 'TA347895'


USD 345.00


Availability*
4 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-1:2000
Reactivity Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-Integrin aV Antibody: A synthesized peptide derived from human Integrin aV
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration 1 mg/ml
Purification Immunogen affinity purified
Predicted Protein Size 116 kDa
Gene Name integrin subunit alpha V
Background The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Synonyms CD51; MSK8; VNRA; VTNR
Note Integrin aV Antibody detects endogenous levels of total Integrin aV
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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ANTIBODY VALIDATION 101
68 Mouse Clones