MUM1 (IRF4) Rat Monoclonal Antibody [Clone ID: IRF4.3E4]

CAT#: TA327948

Rat Monoclonal anti-IRF4 Antibody

Product Images

Western blot analysis of Daudi (lane 1), Raji (lane 2) and A20 (lane 3) cells using IRF4 antibody (clone IRF4.3E4). β-actin antibody (poly6221) was used as loading control.

Specifications

Product Data

• Clone Name: IRF4.3E4
• Applications: WB
• Recommended Dilution: WB, ICFC
• Reactivities: Mouse, Human
• Host: Rat
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: GST fusion protein containing C-terminal of murine IRF4
• Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kD
• Gene Name: interferon regulatory factor 4
• Database Link:
  NP_002451
  Entrez Gene 16364 MouseEntrez Gene 3662 Human
  UniProt ID Q15306
• Background: The IRF family consists of at least nine members. IRF4 and IRF8 are highly homologous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays an essential role in macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.
• Synonyms: LSIRF; MUM1; NF-EM5; SHEP8

Reference Data

• Protein Families: Druggable Genome, Transcription Factors