TRP 7 (TRPC7) Mouse Monoclonal Antibody [Clone ID: S64A-36]

CAT#: TA326454

Mouse Monoclonal Anti-TrpC7 Antibody

Product Images

Western blot analysis of TrpC7 in rat brain membrane lysates using a 1:1000 dilution of the antibody

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  IF analysis of TrpC7 in mouse backskin sections using a dilution of the antibody

Specifications

Product Data

• Clone Name: S64A-36
• Applications: IF, WB
• Recommended Dilution: WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide amino acids 845-862 of human TRPC7
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transient receptor potential cation channel subfamily C member 7
• Database Link:
  NP_065122
  Entrez Gene 26946 MouseEntrez Gene 282822 RatEntrez Gene 57113 Human
  UniProt ID Q9HCX4
• Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulartion by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway . TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure .
• Synonyms: TRP7
• Note: Detects ~100kDa.

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane