EGF Rabbit Polyclonal Antibody

CAT#: TA324063

Anti-EGF Rabbit Polyclonal Antibody

Antibody Service


 Product Datasheet for 'TA324063'

USD 335


Availability*
In Stock

Size
    • 100 ul

Product images

Specifications

Product Data
Applications IHC
Recommend Dilution ELISA: 1:1000-5000, IHC: 1:50-200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 926-1026 amino acids of human epidermal growth factor
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 2.4mg/ml
Purification Antigen affinity purification
Gene Name epidermal growth factor
Background This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth; proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor; epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants
Synonyms HOMG4|URG
Reference Data
Protein Families ES Cell Differentiation/IPS, Transmembrane, Adult stem cells, Embryonic stem cells, Induced pluripotent stem cells, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Regulation of actin cytoskeleton, Pathways in cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.