NMDAR2B (GRIN2B) Rabbit Polyclonal Antibody

CAT#: TA323551

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Anti-GRIN2B Rabbit Polyclonal Antibody



USD 345.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:1000-5000, WB: 1:500-2000
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 1413-1425 amino acids of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 166 kDa
Gene Name glutamate ionotropic receptor NMDA type subunit 2B
Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation; an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1); NR2 (GRIN2A; GRIN2B; GRIN2C; or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.?
Synonyms EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B
Reference Data
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Systemic lupus erythematosus
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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