TLX2 Rabbit Polyclonal Antibody

CAT#: TA319662

Rabbit Polyclonal TLX2 Antibody

Product Images

Western blot analysis of TLX2 in rat brain tissue lysate with TLX2 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of TLX2 in rat brain tissue with TLX2 antibody at 2.5 ug/mL.

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  Immunofluorescence of TLX2 in rat brain tissue with TLX2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2.
• Formulation: TLX2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TLX2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 31 kDa; Observed: 30 kDa
• Gene Name: T-cell leukemia homeobox 2
• Database Link:
  NP_057254
  Entrez Gene 21909 MouseEntrez Gene 680117 RatEntrez Gene 3196 Human
  UniProt ID O43763
• Background: TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
• Synonyms: HOX11L1; NCX

Reference Data

• Protein Families: Transcription Factors