GBA Mouse Monoclonal Antibody [Clone ID: OTI4G4]

CAT#: CF803377

Carrier-free (glycerol/BSA-free) GBA mouse monoclonal antibody, clone OTI4G4 (formerly 4G4)

Formulation: Standard Carrier-Free


  View other "OTI4G4" antibodies (4)

USD 600.00

3 Days*

Size
    • 100 ug

Frequently bought together (1)
Biotinylation Labelling Kit formatted 4 x 0.05mg
    • 200 ug

USD 412.00

Specifications

Product Data
Clone Name OTI4G4
Applications IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 55.5 kDa
Gene Name glucosylceramidase beta
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Synonyms GBA1; GCB; GLUC
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.