CD14 (NM_000591) Human Recombinant Protein

CAT#: TP723883

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Purified recombinant protein of Human CD14 molecule (CD14), transcript variant 1

  View other "CD14" proteins (11)

USD 150.00

5 Days

    • 10 ug

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Product Data
Description Purified recombinant protein of Human CD14 molecule (CD14), transcript variant 1
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence Human CD14, the region of Thr20-Cys352, from gene Accession# NM_000591
Tag Tag Free
Predicted MW 35.8 kDa
Concentration lot specific
Purity >95%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS, pH7.2
Bioactivity The ED50 is 100-400 ng/ml, corresponding to a specific activity of 1.0-2.5 x 104 units/mg, determined by production of IL-8 from THP-1 cells trated with LPS (2 ng/ml) and CD14.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_000582
Locus ID 929
Refseq Size 1623
Cytogenetics 5q31.3
Refseq ORF 1125
Synonyms CD14 antigen; CD14 molecule; monocyte differentiation antigen CD14
Summary The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway


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