CD14 (NM_000591) Human Recombinant Protein

CAT#: TP723883

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Purified recombinant protein of Human CD14 molecule (CD14), transcript variant 1


 Product Datasheet for 'TP723883'

  View other "CD14" proteins (13)

USD 145.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human CD14 molecule (CD14), transcript variant 1
Species Human
Expression Host CHO
Tag Tag Free
Predicted MW 35.8 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >95%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS, pH7.2
Bioactivity The ED50 is 100-400 ng/ml, corresponding to a specific activity of 1.0-2.5 x 104 units/mg, determined by production of IL-8 from THP-1 cells trated with LPS (2 ng/ml) and CD14.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq NP_000582
Locus ID 929
Refseq Size 1623
Cytogenetics 5q31.3
Refseq ORF 1125
Synonyms CD14 antigen; CD14 molecule; monocyte differentiation antigen CD14
Summary The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway

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Other Versions

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CD14 mouse monoclonal antibody,clone OTI9C7
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