RIP3 (RIPK3) (NM_006871) Human Recombinant Protein

CAT#: TP710302

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Purified recombinant protein of Human receptor-interacting serine-threonine kinase 3 (RIPK3), full length, with N-terminal GST and C-terminal His tag, expressed in sf9, 20ug


Product Datasheet for 'TP710302'


  View other "RIPK3" proteins (2)

USD 425.00


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    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Human receptor-interacting serine-threonine kinase 3 (RIPK3), full length, with N-terminal GST and C-terminal His tag, expressed in sf9, 20ug
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC209549, encoding human full-length RIPK3
Tag N-GST
Predicted MW 56.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 300mM NaCl,10% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_006862
Locus ID 11035
Refseq Size 1940
Cytogenetics 14q12
Refseq ORF 1554
Synonyms RIP3
Summary The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cytosolic DNA-sensing pathway

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