Esyt2 (NM_028731) Mouse Recombinant Protein

CAT#: TP518422

Purified recombinant protein of Mouse extended synaptotagmin-like protein 2 (Esyt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR218422 representing NM_028731
  Red=Cloning site Green=Tags(s)
  
  MSSAGGEGPEAGPGRAGGRSEPEAPGSALSVDLPGLLGQLARSFALLLPVYALGYLGLSFSWVLLALGLL
  AWCRRSRGLKASRLCRALALLEDEEQAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKL
  FRETIEPAVRGANAHLSTFSFTKVDVGQQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYF
  CRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIIS
  NYLVLPNRITVPLVSEVQIAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQ
  SKVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFTLDEVPK
  GKLHLKLEWLTLMPDAANLDKVLADIRADKDQASDGLSSALLILYLDSARNLPSGKKINSNPNPLVQMSV
  GHKAQESKIRYKTSEPVWEENFTFFIHNPRRQDLEVEVKDEQHQCSLGSLRIPLSQLLTSDNMTINQRFQ
  LSNSGPNSTLKMKIALRVLHLEKQERPPDYQHSAQVKRPSVSKEGRKMPIKSQMSASPGTGGANTAPSTP
  VMGVDDKPAMEEKPQPPEASPLGHRDLGRSSSSLLASPSHIAAKEPTPSIASDISLPIATQELRQRLRQL
  ENGTTLGQSPLGQIQLTIRHSSQRNKLIVVVHSCRNLIAFSEDGSDPYVRMYLLPDKRRSGRRKTHVSKK
  TLNPVFDQSFDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVVLASEELAKGWTQWYDLTEDGTR
  PQVIT
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 94.6 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_083007
• Locus ID: 52635
• UniProt ID: Q3TZZ7
• Cytogenetics: 12 62.65 cM
• Refseq Size: 5556
• Refseq ORF: 2535
• Synonyms: 2410017M09Rik; 4921504I16Rik; CHR2SYT; D12Ertd551e; Fam62b
• Summary: Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex (By similarity).[UniProtKB/Swiss-Prot Function]