Lmcd1 (NM_144799) Mouse Recombinant Protein
SKU
TP505613
Purified recombinant protein of Mouse LIM and cysteine-rich domains 1 (Lmcd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
$1,020.00
4 Weeks*
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 41 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_659048 |
| Locus ID | 30937 |
| UniProt ID | Q8VEE1 |
| Cytogenetics | 6 E3 |
| RefSeq Size | 1742 |
| RefSeq ORF | 1095 |
| Synonyms | AW455500; AW553074; dyxin |
| Summary | Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Citations
Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation
Ansseau, Eidahl, Lancelot et al
PLoS ONE (2016) 11 (1), e0146893 DOI: 10.1371/journal.pone.0146893
Ansseau, Eidahl, Lancelot et al
PLoS ONE (2016) 11 (1), e0146893 DOI: 10.1371/journal.pone.0146893
Cited by 53
AI Summary: OriGene’s Myc-DDK-tagged expression plasmids for SRSF9 (pCMV6.SRSF9), RBM3 (pCMV6.RBM3), and LMCD1 (pCMV6.LMCD1) were used to express these proteins in HEK293 cells, enabling the identification and validation of their interactions with DUX4 and DUX4c during muscle differentiation.
Snippet: HEK293 cells were transfected (Life Technologies Lipofectamine 2000 transfection reagent) with Myc-DDK-tagged-human serine/arginine-rich splicing factor 9 (pCMV6.SRSF9, OriGene), Myc-DDK-tagged-human RNA-binding motif protein 3 (pCMV6.RBM3, OriGene), Myc-DKK-tagged-human LIM and cysteine-rich domains 1 (pCMV6.LMCD1, Origene) or AAV6.DUX4.V5 expression plasmids and harvested 24 h post-transfection. …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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