GRIA1 (NM_001114183) Human Recombinant Protein

CAT#: TP326253

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Recombinant protein of human glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 2


Product Datasheet for 'TP326253'


 Cited in 2 publications.

  View other "GRIA1" proteins (5)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 2
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC226253. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 101.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity In vitro ubiquitination assay substrate (PMID: 28212375)
In vitro ubiquitination assay substrate (PMID: 29771335)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001107655
Locus ID 2890
Cytogenetics 5q33.2
Refseq ORF 2718
Synonyms GluA1; GLUH1; GLUR1; GLURA; HBGR1
Summary Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Amyotrophic lateral sclerosis (ALS), Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction

Citations (2)

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