EP4 (PTGER4) (NM_000958) Human Recombinant Protein

CAT#: TP310932

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Recombinant protein of human prostaglandin E receptor 4 (subtype EP4) (PTGER4)


 Product Datasheet for 'TP310932'

  View other "PTGER4" proteins (2)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human prostaglandin E receptor 4 (subtype EP4) (PTGER4)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 52.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000949
Locus ID 5734
Refseq Size 3432
Cytogenetics 5p13.1
Refseq ORF 1464
Synonyms EP4; EP4R
Summary The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction

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Other Versions

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