SHMT1 (NM_148918) Human Recombinant Protein

CAT#: TP305102

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Recombinant protein of human serine hydroxymethyltransferase 1 (soluble) (SHMT1), transcript variant 2


 Product Datasheet for 'TP305102'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human serine hydroxymethyltransferase 1 (soluble) (SHMT1), transcript variant 2
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC205102. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 48.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_683718
Locus ID 6470
Refseq Size 2436
Cytogenetics 17p11.2
Refseq ORF 1332
Synonyms CSHMT; SHMT
Summary This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Protein Pathways Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Methane metabolism, One carbon pool by folate

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101