KEAP1 (NM_203500) Human Recombinant Protein

CAT#: TP302189

Recombinant protein of human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1

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 Product Datasheet for 'TP302189'

USD 680.00


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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC202189. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 69.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_987096
Locus ID 9817
Refseq Size 2606
Cytogenetics 19p13.2
Refseq ORF 1872
Synonyms INrf2; KLHL19
Summary This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
Protein Families
Protein Pathways
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