CD18 / ITGB2 (23-700, His-tag)

USD 400.00


Availability*
2 Weeks

Size
    • 50 ug


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Specifications

Product Data
Species Human
Expression Host Other
Tag His-tag
Predicted MW 75.9 kDa
Concentration 0.25 mg/ml (determined by absorbance at 280nm)
Purity > 85 % by SDS - PAGE
Buffer Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Endotoxin < 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation Liquid purified protein
Reference Data
RefSeq NP_000202
Locus ID 3689
Cytogenetics 21q22.3
Synonyms CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Summary This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones