GNRH1 / Progonadoliberin-1 (24-92, His-tag) Human Protein

CAT#: AR51532PU-S

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GNRH1 / Progonadoliberin-1 (24-92, His-tag) human recombinant protein, 0.1 mg


Product Datasheet for 'AR51532PU-S'


USD 415.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description GNRH1 / Progonadoliberin-1 (24-92, His-tag) human recombinant protein, 0.1 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MGSQHWSYGL RPGGKRDAEN LIDSFQEIVK EVGQLAETQR FECTTHQPRS PLRDLKGALE SLIEEETGQK KI
Tag His-tag
Predicted MW 10.3 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity >90% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Preparation Liquid purified protein
Protein Description Recombinant human GNRH1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000816
Locus ID 2796
Cytogenetics 8p21.2
Synonyms GNRH; GRH; LHRH; LNRH
Summary This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways GnRH signaling pathway

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