HLA class II DO alpha / HLA-DOA (26-217, His-tag) Human Protein
CAT#: AR51010PU-N
HLA class II DO alpha / HLA-DOA (26-217, His-tag) human protein, 0.5 mg
Size: 100 ug
Other products for "HLA-DOA"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME
|
Tag | His-tag |
Predicted MW | 24.1 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Presentation | Purified |
Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_002110 |
Locus ID | 3111 |
UniProt ID | P06340, X5CF87, A0A1V0E3Q8, A0A1V0E3S6, A0A1V0E3R8, A0A1V0E3Q1, A0A1V0E3N6, A0A1V0E3Q3, A0A1V0E3P3, A0A1V0E3N7, A0A1V0E3S4, A0A1V0E3Q4, A0A1V0E3R4, A0A1V0E3P8, A0A1V0E3R0, A0A1V0E3R3, A0A1V0E3N1, A0A1V0E3Q7, A0A1V0E3R6, A0A1V0E3N3, A0A1V0E3P0, A0A1V0E3Q5, A0A1V0E3P1, A0A1V0E3M7, A0A1V0E3P9, A0A1V0E3P6, A0A1V0E3Q2, A0A1V0E3T1, A0A1V0E3S0, A0A1V0E3S7, A0A1V0E3Q6 |
Cytogenetics | 6p21.32 |
Synonyms | MHC class II antigen DOA, MHC DZ alpha, MHC DN-alpha, HLA-DNA, HLA-DZA |
Summary | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] |
Protein Families | Transmembrane |
Protein Pathways | Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
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