IFNG / Interferon gamma (24-161, His-tag)

CAT#: AR50317PU-S

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Recombinant human IFNG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.


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USD 330.00


Availability*
2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human IFNG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 18.5 kDa
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer Phosphate buffered saline (pH 7.4)
Preparation Liquid purified protein
Reference Data
RefSeq NP_000610
Locus ID 3458
Cytogenetics 12q15
Synonyms IFG; IFI
Summary This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

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68 Mouse Clones