Interleukin-1 alpha / IL-1A (113-271, His-tag) Human Protein

CAT#: AR09045PU-N

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Interleukin-1 alpha / IL-1A (113-271, His-tag) human recombinant protein, 50 µg



USD 363.00


Availability*
3 Weeks

Size
    • 50 ug


Product images

Specifications

Product Data
Description Interleukin-1 alpha / IL-1A (113-271, His-tag) human recombinant protein, 50 µg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA
Tag His-tag
Predicted MW 22.4 kDa
Concentration lot specific
Purity >90% > 90% by SDS PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl pH 7.5, 10% glycerol
Preparation Liquid purified protein
Protein Description Recombinant IL-1a protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000566
Locus ID 3552
UniProt ID P01583
Cytogenetics 2q14.1
Synonyms IL-1A; IL1; IL1-ALPHA; IL1F1
Summary The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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