Cofilin-1 (1-166, His-tag) Human Protein

CAT#: AR09012PU-L

Reviews ()
Write a review

Cofilin-1 (1-166, His-tag) human recombinant protein, 0.5 mg



USD 1,105.00


Availability*
2 Weeks

Size
    • 500 ug


Product images

Specifications

Product Data
Description Cofilin-1 (1-166, His-tag) human recombinant protein, 0.5 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA EKLGGSAVIS LEGKPL
Tag His-tag
Predicted MW 20 kDa
Concentration 1.0 mg/ml
Purity >95% >/= 95% by SDS PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris pH 8.0, 10 % Glycerol
Preparation Liquid purified protein
Protein Description Recombinant human Cofilin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Note NCBI Accession : NP _005498
Storage Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_005498
Locus ID 1072
Cytogenetics 11q13.1
Synonyms CFL; cofilin; HEL-S-15
Summary The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. [supplied by OMIM, Apr 2004]
Protein Families Druggable Genome
Protein Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton

Documents

Other products for "CFL1"
Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
Molbio tools