CCDC134 (NM_024821) Human Mass Spec Standard

CAT#: PH304377

CCDC134 MS Standard C13 and N15-labeled recombinant protein (NP_079097)

Product Images

Coomassie blue staining of purified CCDC134 protein (Cat# TP304377). The protein was produced from HEK293T cells transfected with CCDC134 cDNA clone (Cat# RC204377) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC204377
• Predicted MW: 26.6 kDa
• Protein Sequence:
  Sequence Link

  >RC204377 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MDLLQFLAFLFVLLLSGMGATGTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVML
  KGLFKVLEDSRTVLTAADVLPDGPFPQDEKLKDAFSHVVENTAFFGDVVLRFPRIVHYYFDHNSNWNLLI
  RWGISFCNQTGVFNQGPHSPILSLMAQELGISEKDSNFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKE
  EKRKEIRKGPRISRSQSEL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_079097
• RefSeq Size: 1279
• RefSeq ORF: 687
• Locus ID: 79879
• UniProt ID: Q9H6E4
• Cytogenetics: 22q13.2
• Summary: In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808).[UniProtKB/Swiss-Prot Function]
• Protein Families: Secreted Protein