Serglycin (SRGN) Human Gene Knockout Kit (CRISPR)
CAT#: KN202118BN
SRGN - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | Serglycin |
Locus ID | 5552 |
Components |
KN202118G1, Serglycin gRNA vector 1 in pCas-Guide CRISPR vector KN202118G2, Serglycin gRNA vector 2 in pCas-Guide CRISPR vector KN202118BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001321053, NM_001321054, NM_002727, NR_036430 |
UniProt ID | P10124 |
Synonyms | PPG; PRG; PRG1 |
Summary | This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN202118 | SRGN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN202118LP | SRGN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN202118RB | SRGN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN402118 | SRGN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
|
GA103748 | SRGN CRISPRa kit - CRISPR gene activation of human serglycin |
USD 1,657.00 |
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