Human KDM1A activation kit by CRISPRa

CAT#: GA107980

KDM1A CRISPRa kit - CRISPR gene activation of human lysine demethylase 1A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KDM1A
• Locus ID: 23028
• Kit Components:

  GA107980G1, KDM1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107980G2, KDM1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107980G3, KDM1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001009999, NM_015013, NM_001363654
• UniProt ID: O60341
• Synonyms: AOF2; BHC110; CPRF; KDM1; LSD1
• Summary: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]