STAM1 (STAM) (NM_003473) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC219230L3V

Lenti ORF particles, STAM (Myc-DDK tagged) - Human signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (STAM), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: STAM1
• Synonyms: STAM-1; STAM1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_003473
• ORF Size: 1620 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219230).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003473.2
• RefSeq Size: 2967 bp
• RefSeq ORF: 1623 bp
• Locus ID: 8027
• UniProt ID: Q92783
• Cytogenetics: 10p12.33
• Domains: SH3, VHS, UIM
• Protein Pathways: Endocytosis, Jak-STAT signaling pathway
• MW: 59 kDa
• Gene Summary: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]