XRCC3 (NM_005432) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200326L4V

Lenti ORF particles, XRCC3 (mGFP-tagged) - Human X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: XRCC3
• Synonyms: CMM6
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005432
• ORF Size: 1038 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200326).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005432.2
• RefSeq Size: 2620 bp
• RefSeq ORF: 1041 bp
• Locus ID: 7517
• UniProt ID: O43542
• Cytogenetics: 14q32.33
• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination
• MW: 37.8 kDa
• Gene Summary: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]