Eomes (NM_010136) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210179L3V

Lenti ORF particles, Eomes (Myc-DDK-tagged) - Mouse eomesodermin homolog (Xenopus laevis) (Eomes), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Eomes
• Synonyms: C77258; TBR-2; Tbr2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_010136
• ORF Size: 2121 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210179).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010136.2, NP_034266.2
• RefSeq Size: 3731 bp
• RefSeq ORF: 2124 bp
• Locus ID: 13813
• UniProt ID: O54839
• Cytogenetics: 9 F3
• Gene Summary: Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.[UniProtKB/Swiss-Prot Function]