CDS2 (NM_003818) Human Untagged Clone

CAT#: SC324271

CDS2 (untagged)-Human CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (CDS2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDS2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003818.2 GCTCCGGCGGCTTCGCTGCTAGCTCGCGGCGACGTCGGGCCGATTTTCCCAGGATGACAG
  AGCTGAGGCAGAGGGTGGCCCATGAGCCGGTTGCGCCACCCGAGGACAAGGAGTCAGAGT
  CAGAAGCAAAGGTAGATGGAGAGACTGCATCGGACAGTGAGAGCCGGGCAGAATCCGCAC
  CCCTGCCAGTCTCTGCAGATGATACCCCGGAGGTCCTCAATAGGGCCCTTTCCAACTTGT
  CTTCAAGATGGAAGAACTGGTGGGTGAGAGGCATCCTGACTTTGGCCATGATTGCATTTT
  TCTTCATCATCATTTACCTGGGACCAATGGTTTTGATGATAATCGTGATGTGCGTTCAGA
  TTAAGTGTTTCCATGAGATAATCACTATTGGCTACAACGTCTACCACTCATATGATCTGC
  CCTGGTTCAGGACGCTCAGCTGGTACTTTCTCCTGTGTGTAAACTATTTCTTCTATGGTG
  AGACAGTGACGGATTACTTCTTCACCCTGGTCCAGAGAGAAGAGCCTTTGCGGATTCTCA
  GTAAATACCACCGGTTCATTTCCTTTACTCTCTATCTAATAGGATTCTGCATGTTTGTAC
  TGAGTCTGGTCAAGAAGCATTATCGACTGCAGTTCTACATGTTTGGCTGGACCCATGTGA
  CATTGCTGATTGTTGTAACACAGTCACATCTTGTTATCCACAACCTATTTGAAGGAATGA
  TCTGGTTCATTGTCCCCATATCTTGTGTGATCTGTAATGACATCATGGCCTATATGTTTG
  GCTTTTTCTTTGGTCGGACCCCACTCATCAAGCTGTCCCCGAAGAAGACCTGGGAAGGCT
  TCATTGGGGGCTTCTTTGCTACTGTGGTGTTTGGCCTTCTGCTGTCCTATGTGATGTCCG
  GGTACAGATGCTTTGTCTGCCCTGTGGAGTACAACAATGACACCAACAGCTTCACTGTGG
  ACTGTGAGCCCTCGGACCTGTTTCGCCTGCAGGAGTACAACATTCCTGGGGTGATCCAGT
  CAGTCATTGGCTGGAAAACGGTCCGGATGTACCCCTTCCAGATTCACAGCATCGCTCTCT
  CCACCTTTGCCTCGCTCATTGGCCCCTTTGGAGGATTCTTCGCAAGTGGATTCAAACGAG
  CCTTTAAAATCAAAGACTTTGCCAATACCATTCCTGGCCATGGAGGCATCATGGATCGCT
  TTGACTGCCAGTATCTGATGGCCACCTTTGTCAATGTATACATCGCCAGTTTTATCAGAG
  GCCCTAACCCAAGCAAACTGATTCAGCAGTTCCTGACTTTACGGCCAGATCAGCAGCTCC
  ACATCTTCAACACGCTGCGGTCTCATCTGATCGACAAAGGGATGCTGACATCCACCACAG
  AGGACGAGTAGGGGCCACCCAGGGCCAGGAGAACAGGAACAGAACTGAGCAGGGGCAGGT
  CTCCAAGAAATCCCTGCTTGGAGCTGCAGAAGGGTTGCCTTCTGTAGGTCGGAGGAATGG
  AGGCTTACTAACCAGGTAAGCCTTCTATGCATCCACACCAAAATCCTGCAGAATGTAAGT
  AAGCTCTGCTTTATAAGATGGGTTCACCTTCATCGCAGACTGAAAGTTTCAGTTTTTATT
  TTTTTCAGAAAGCACGAAAAATTATTTATAATAGTCTGGAGAAAAAACACACTGTAATAT
  TTCAAGTGTATGCAGTAGAATGTACTGTAACTGAGCCCTTTCCCACATGTCTAGGCTCCA
  ATGTCTCCTGTAGGTCCACCTAACTGTGTGTTTTCAGGGACAATGCCATCCATGTTTGTG
  CTGTAGACTTGCTGCTGCTGAATCCTTTCTGGGGACTTTCTCATCGGGCAGGGAGCAGAG
  GGCTTCTCGTTCATGCACCCTTTGCCTGAACACCCATGTAGCTGCTGTGTTGTGTATATA
  TTACTCTTAAGAGGAGTGTGTGTGTCTGTGTTTGTTTTAAAAGTCACTTATTTCTTACAG
  TGATTTCAATTGCACCATGACTTCTTCACTAAAACCACAAAGTCCTGCTTAAAACTATGG
  AAAACCTAACCTGATTAGAGCCTTGACTATTTTGAAGATTAAATGCACACTTTTTATATA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003818
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003818.2, NP_003809.1
• RefSeq Size: 2711 bp
• RefSeq ORF: 1338 bp
• Locus ID: 8760
• UniProt ID: O95674
• Cytogenetics: 20p12.3
• Domains: CTP_transf_1
• Protein Families: Transmembrane
• Protein Pathways: Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]