THEM4 (NM_053055) Human Untagged Clone

CAT#: SC321964

THEM4 (untagged)-Human thioesterase superfamily member 4 (THEM4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: THEM4
• Synonyms: CTMP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC321964 GGGGTTAACTCGCACGCGCGCTCTTGTGGCGGAGGTAGAGTGCGCCGTCCAGGGCTAGAG
  CAAGCGCGGCCCCGCGGCCCGGAGCCATGCTGAGGAGCTGCGCCGCGCGCCTCCGCACGC
  TGGGGGCTCTGTGCCGGCCGCCAGTAGGCCGGCGCCTGCCGGGAAGCGAGCCGCGACCCG
  AGCTGAGGTCATTTTCTTCTGAGGAAGTCATTCTTAAGGACTGTTCTGTCCCCAACCCCA
  GCTGGAACAAGGACCTAAGACTGCTCTTTGACCAGTTTATGAAGAAATGTGAAGATGGCT
  CCTGGAAACGTTTGCCTTCATATAAACGTACACCTACTGAATGGATTCAAGACTTCAAAA
  CCCATTTTCTTGACCCAAAGCTTATGAAAGAAGAACAAATGTCACAGGCCCAGCTCTTCA
  CCAGAAGCTTTGATGATGGCCTGGGCTTTGAATACGTGATGTTCTACAATGACATTGAGA
  AAAGGATGGTTTGCTTATTTCAAGGAGGCCCTTACCTGGAAGGACCACCTGGATTCATTC
  ATGGAGGTGCCATTGCAACCATGATTGATGCTACTGTTGGTATGTGTGCAATGATGGCTG
  GGGGAATCGTCATGACTGCCAATCTCAACATCAATTATAAAAGACCTATCCCTCTTTGTT
  CTGTTGTTATGATAAATAGCCAACTTGATAAAGTTGAAGGAAGGAAATTTTTTGTTTCCT
  GTAATGTTCAGAGTGTTGATGAGAAGACCCTATACTCAGAGGCGACAAGCTTATTTATAA
  AGCTGAATCCTGCTAAAAGTCTGACATAAAGAGCTGCTGGTGAACTCCATCTCATTCTCG
  CCCCTCCAGAAGAAGCAGTTGTCCCCCAAATACTCTGCTCCCTCACTGCTGAATCCCTGT
  AGGGAGAAGCCTGCCAACAGTGACCTTCCGAAACAGCCTTCTGAATACAAAGAGGATTCA
  GTTTCCATCTTCTCAACTTTTTAACACAGAAACACTTCCTGCGAGCATATCGACAACTCT
  CGGGCCAGGCGCTGTGGCTCACACCTATAATCCCAGCACTTTAGGAGGCCGAGGCAGGCG
  GATTGCCTGAGCTCAGGAGTTCAAGATCAGTCTGGGCAACACGATGAAACTCCGTCTCTA
  CTAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_053055
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_053055.3, NP_444283.2
• RefSeq Size: 2224 bp
• RefSeq ORF: 723 bp
• Locus ID: 117145
• UniProt ID: Q5T1C6
• Cytogenetics: 1q21.3
• Domains: 4HBT
• Protein Families: Druggable Genome
• Gene Summary: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).