MAML3 (NM_018717) Human Untagged Clone

CAT#: SC315211

MAML3 (untagged)-Human mastermind-like 3 (Drosophila) (MAML3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAML3
• Synonyms: CAGH3; ERDA3; GDN; MAM-2; mam-3; MAM2; TNRC3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC315211 representing NM_018717.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGGGGATTTCGCAGCCCCCGCTGCTGCCGCGAATGGCAGTAGTATTTGCATCAACAGTAGCCTGAAC
  AGCAGCCTCGGCGGGGCCGGGATCGGTGTGAATAATACTCCCAATAGTACTCCCGCTGCTCCGAGTAGC
  AATCACCCGGCAGCCGGTGGATGCGGCGGCTCCGGGGGCCCCGGCGGCGGTTCGGCGGCCGTTCCCAAG
  CACAGCACCGTGGTGGAGCGGCTCCGCCAGCGCATCGAGGGCTGCCGTCGGCACCACGTCAACTGCGAG
  AACAGGTACCAGCAGGCTCAGGTGGAGCAGCTGGAGCTGGAGCGCCGGGACACCGTGAGCCTCTACCAG
  CGGACCCTGGAGCAGAGGGCCAAGAAATCGGGCGCCGGCACCGGCAAACAGCAGCACCCGAGCAAACCC
  CAGCAAGATGCGGAGGCTGCCTCGGCGGAGCAGAGGAACCACACGCTGATCATGCTACAAGAGACTGTG
  AAAAGGAAGTTGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAAT
  TTTTCTCCGACTAGCAAACGAATTCGAAAGGACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCC
  AGTAACATGCCACTGCCTTCAGCTTCTCCTCTTCACCAACTTGACCTGAAACCTTCTTTGCCCTTGCAG
  AACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAATGGTAGGCTCCCTGAGATTAAA
  CTTCCTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAA
  GAACCTCTCGATGACCCTACTTGCATAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTC
  TCAGACATTAATCTGAATGATCAGGAGTGGCAAGAATTAATAGATGAATTGGCCAACACGGTTCCTGAG
  GATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAGAAGGAGCCAGAATTCTCGCAGCCAGCA
  ACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTCGCACAT
  GTCTCCATGGGATCTCCCCAGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCC
  ACTAGTTTACCTTCTGTTGCCAGCACTCCCGCAGCTCCAAACCCTGCAAGCTCACCAGCAAACTGTGCT
  GTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACTCCAGGCCAAGCTCCACCTCGGCCTGGAAATGGT
  TATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCTGTGCCCAGCTCT
  GACATGTCTCCAGCAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAG
  CAGAAACAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAG
  CACTCAAATCAGACTTCAAATTGGTCTCCCTTAGGACCTCCCTCTAGTCCATATGGAGCAGCTTTTACT
  GCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCCTTTAACAACCAAAACCCTATAGTGCCTCCA
  ATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAATATGATCAAT
  CAGCAGCCAAATAACTTGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACT
  AAACCCCTGACCCACTTCAATGCAGACCTGAGTCAGAGGATGACACCACCAGTGGCCAACCCCAACAAA
  AACCCCTTGATGCCGTATATCCAGCAGCAGCAACAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAG
  CAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGACCAGAAACGCCTGCTT
  CTCATGAAGCAGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGGAG
  CAGCATCCAGTTGGACTTCCCCGAACCACAGGCCCCATGCAGTCCTCCGTGCCCCCAGGCTCAGGTGGC
  ATGGTCTCAGGAGCCAGTCCCGCAGGCCCCGGCTTCCTGGGCAGCCAGCCCCAAGCAGCCATCATGAAG
  CAGATGCTCATTGATCAGCGGGCCCAGTTGATAGAGCAGCAGAAGCAACAGTTCCTGCGGGAGCAAAGG
  CAGCAGCAGCAGCAGCAGCAGCAGATTTTGGCGGAACAGCAGTTGCAGCAATCACATCTACCCCGGCAG
  CACCTCCAGCCACAGCGGAATCCATACCCAGTGCAGCAGGTCAATCAGTTTCAAGGTTCTCCCCAGGAT
  ATAGCAGCCGTAAGAAGCCAAGCAGCCCTCCAGAGCATGCGAACGTCACGGCTGATGGCACAGAACGCA
  GGCATGATGGGAATAGGACCCTCCCAGAACCCTGGGACGATGGCCACCGCAGCTGCGCAGTCGGAGATG
  GGACTGGCCCCTTATAGCACCACGCCTACCAGCCAACCAGGAATGTACAATATGAGCACAGGCATGACC
  CAAATGTTGCAGCATCCAAACCAAAGTGGCATGAGCATCACACATAACCAAGCCCAGGGACCGAGGCAA
  CCTGCCTCTGGGCAGGGGGTTGGAATGGTGAGTGGCTTTGGTCAGAGCATGCTGGTGAACTCAGCCATT
  ACCCAGCAACATCCACAGATGAAAGGGCCAGTAGGCCAGGCCTTGCCTAGGCCCCAAGCCCCTCCAAGG
  CTGCAGAGCCTTATGGGAACAGTCCAGCAAGGAGCACAAAGCTGGCAACAGAGGAGCTTGCAGGGCATG
  CCTGGGAGGACTAGTGGAGAATTGGGACCATTCAACAATGGCGCCAGCTACCCTCTTCAAGCTGGGCAG
  CCGAGACTGACCAAGCAGCACTTCCCACAGGGACTGAGCCAGTCAGTCGTGGATGCTAACACGGGCACA
  GTGAGGACCCTCAACCCAGCTGCCATGGGTCGGCAGATGATGCCATCGCTCCCGGGGCAGCAAGGCACC
  AGCCAGGCGAGGCCAATGGTCATGTCTGGCCTGAGCCAGGGAGTCCCAGGCATGCCAGCGTTCAGCCAG
  CCCCCAGCACAGCAGCAGATACCCAGTGGCAGCTTTGCTCCAAGCAGCCAGAGCCAAGCCTATGAGCGG
  AATGCCCCTCAGGACGTGTCATACAATTACAGTGGCGACGGAGCTGGGGGTTCCTTCCCTGGCCTCCCG
  GACGGTGCAGACCTTGTGGACTCCATCATCAAAGGCGGGCCAGGGGACGAGTGGATGCAGGAGCTTGAT
  GAATTGTTTGGTAACCCCTAA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018717
• Insert Size: 3402 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_018717.4
• RefSeq Size: 7086 bp
• RefSeq ORF: 3402 bp
• Locus ID: 55534
• UniProt ID: Q96JK9
• Cytogenetics: 4q31.1
• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway
• MW: 121.7 kDa
• Gene Summary: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.[UniProtKB/Swiss-Prot Function]