TXNDC11 (NM_015914) Human Untagged Clone

CAT#: SC314994

TXNDC11 (untagged)-Human thioredoxin domain containing 11 (TXNDC11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TXNDC11
• Synonyms: EFP1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC314994 representing NM_015914.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGTCGGAATGCGGAGGCCGCGGCGGCGGCAGCAGCAGCAGCGAGGACGCCGAGGACGAGGGAGGGGGC
  GGCGGCGGCCCCGCGGGCTCAGACTGCCTCAGCTCGAGCCCGACCCTGGCCACAGCGTCCTCGGCGGGC
  CGGCTCCGTCGCGGGCTGCGTGGCGCCTTCCTCATGGCGCGCCAGCGGCCGGAGCTGCTCTGCGGGGCC
  GTGGCGCTCGGCTGCGCGCTGCTCCTCGCCCTCAAGTTCACCTGCAGTCGAGCAAAAGATGTGATAATA
  CCAGCAAAGCCACCTGTCAGCTTTTTCTCCTTGAGGTCTCCAGTCCTTGACCTCTTCCAGGGGCAGCTG
  GATTATGCAGAGTACGTTCGACGGGATTCAGAGGTGGTACTGCTCTTCTTCTATGCCCCTTGGTGTGGA
  CAGTCCATCGCTGCCAGGGCAGAAATTGAGCAAGCAGCAAGTCGGCTTTCAGATCAGGTGTTGTTTGTG
  GCAATTAACTGTTGGTGGAACCAGGGGAAATGCAGAAAACAGAAACACTTCTTTTATTTTCCTGTAATA
  TATCTGTATCATCGGAGTTTTGGACCAATCGAATACAAAGGCCCCATGAGTGCTGTTTACATTGAGAAG
  TTTGTCCGCCGGGTGATGAAACCACTTCTCTACATCCCATCTCAATCAGAATTACTAGATTTTCTCTCA
  AACTACGAGCCTGGAGTACTCGGGTACTTTGAGTTCAGTGGCTCACCCCAGCCTCCTGGTTATTTGACC
  TTCTTCACCTCAGCATTACATTCATTAAAGAAAGATTACCTAGGAACAGTACGATTTGGGGTTATCACA
  AATAAACATCTTGCGAAACTGGTATCCTTAGTACACTCTGGAAGTGTGTATTTACATAGACATTTCAAC
  ACATCACTTGTCTTCCCCAGGGAGGTCCTGAACTACACAGCTGAGAACATCTGTAAGTGGGCCTTAGAA
  AACCAGGAGACGCTCTTTCGGTGGCTGCGGCCACACGGAGGCAAGAGTCTCCTGCTGAATAACGAGCTG
  AAGAAAGGACCAGCGCTGTTTCTGTTCATACCTTTTAATCCCCTGGCCGAAAGTCATCCTTTAATAGAC
  GAGATCACCGAAGTGGCCTTGGAGTACAACAACTGTCATGGGGACCAGGTGGTGGAGCGTCTCCTTCAG
  CACCTGCGGCGGGTGGATGCTCCAGTGCTGGAGTCCCTGGCCCTGGAAGTGCCGGCACAGCTGCCAGAC
  CCGCCAACGATCACAGCGTCCCCCTGCTGCAACACTGTGGTGCTGCCCCAGTGGCACTCCTTCTCCAGG
  ACCCACAACGTCTGTGAACTCTGTGTCAACCAGACCTCCGGGGGCATGAAGCCGAGCTCGGTCAGCGTG
  CCACAGTGCAGCTTTTTTGAAATGGCAGCAGCTCTGGATTCTTTCTACCTCAAGGAGCAGACCTTTTAT
  CATGTGGCATCAGACAGCATAGAATGCAGCAATTTTTTAACTTCCTATAGCCCCTTCAGCTACTACACT
  GCATGTTGCAGGACCATAAGCAGGGGTGTGTCAGGCTTCATCGACTCTGAACAAGGTGTCTTTGAAGCC
  CCTACTGTTGCATTTTCTTCCCTTGAGAAGAAATGTGAGGTTGATGCCCCAAGCTCCGTTCCTCACATT
  GAGGAGAACAGGTATCTCTTTCCAGAAGTGGACATGACTAGCACAAACTTCACAGGCCTGAGCTGCAGA
  ACCAACAAGACTCTCAACATCTACCTTTTGGATTCAAATTTGTTTTGGTTATATGCAGAGAGACTGGGT
  GCTCCGAGCTCCACTCAGGTGAAAGAATTTGCGGCAATTGTTGACGTGAAAGAAGAATCTCATTACATC
  TTGGATCCAAAGCAAGCACTGATGAAGCTCACCCTAGAGTCTTTTATTCAAAACTTCAGCGTTCTCTAT
  AGTCCCTTGAAAAGGCATCTCATTGGAAGTGGCTCTGCCCAGTTCCCGTCTCAGCATTTAATCACTGAA
  GTGACAACTGATACCTTTTGGGAAGTAGTCCTTCAAAAACAGGACGTTCTCCTGCTCTATTACGCTCCG
  TGGTGCGGCTTCTGTCCATCCCTCAATCACATCTTCATCCAGCTAGCTCGGAACCTGCCCATGGACACA
  TTCACTGTGGCAAGGATTGACGTGTCTCAGAATGACCTTCCTTGGGAATTTATGGTCGATCGTCTTCCT
  ACTGTCTTGTTTTTTCCCTGCAACAGAAAGGACCTAAGTGTGAAATACCCCGAAGACGTCCCCATCACC
  CTTCCAAACCTGTTGAGGTTCATTTTGCATCACTCAGACCCTGCTTCCAGCCCCCAGAATGTGGCTAAC
  TCTCCTACCAAGGAGTGTCTTCAGAGCGAGGCAGTCTTACAGCGGGGGCACATCTCCCACTTGGAGAGA
  GAGATCCAGAAACTGAGAGCAGAAATAAGCAGCCTCCAGCGAGCACAAGTGCAGGTGGAGTCCCAGCTC
  TCCAGTGCCCGCAGAGATGAGCACCGGCTGCGGCAGCAGCAGCGGGCCCTGGAAGAGCAGCACAGCCTG
  CTCCACGCACACAGTGAGCAGCTGCAGGCCCTCTATGAGCAGAAGACACGTGAGCTGCAGGAGCTGGCC
  CGCAAGCTGCAGGAGCTGGCCGATGCCTCAGAAAACCTCCTTACCGAGAACACGTGGCTCAAGATCCTG
  GTGGCGACCATGGAGAGGAAACTGGAGGGCAGGGATGGAGCTGAAAGCCTGGCGGCCCAGAGAGAGGTC
  CACCCCAAGCAGCCTGAGCCCTCAGCCACCCCCCAGCTCCCTGGCAGCTCCCCTCCACCTGCCAATGTC
  AGCGCCACACTGGTGTCTGAAAGGAATAAGGAGAACAGGACAGACTAA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015914
• Insert Size: 2877 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015914.6
• RefSeq Size: 3164 bp
• RefSeq ORF: 2877 bp
• Locus ID: 51061
• UniProt ID: Q6PKC3
• Cytogenetics: 16p13.13
• Domains: thiored
• Protein Families: Druggable Genome
• MW: 107.5 kDa
• Gene Summary: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.[UniProtKB/Swiss-Prot Function]