SLC6A11 (NM_014229) Human Untagged Clone

CAT#: SC310207

SLC6A11 (untagged)-Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC6A11
• Synonyms: GAT-3; GAT3; GAT4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014229 edited
  CATGACGGCGGAGAAGGCGCTGCCCCTGGGCAATGGGAAGGCTGCTGAGGAGGCGCGGGA
  GTCCGAGGCGCCGGGTGGCGGCTGCAGCAGCGGGGGCGCGGCGCCCGCGCGCCACCCGCG
  CGTCAAGCGCGACAAGGCGGTCCACGAGCGCGGCCACTGGAACAACAAGGTGGAGTTCGT
  GCTGAGCGTGGCCGGGGAGATCATTGGGCTGGGCAACGTGTGGCGCTTCCCCTACCTGTG
  CTACAAGAACGGAGGAGGGGCATTCCTGATTCCCTACGTGGTGTTTTTTATTTGCTGTGG
  AATTCCTGTTTTTTTCCTGGAGACAGCTCTGGGGCAGTTCACAAGTGAAGGTGGCATTAC
  GTGTTGGAGGAAAGTTTGCCCTTTATTTGAAGGCATTGGCTATGCAACACAGGTGATTGA
  GGCCCATCTGAATGTGTACTACATCATCATCCTGGCATGGGCCATTTTTTACCTGAGCAA
  CTGCTTCACTACTGAGCTACCCTGGGCTACCTGTGGGCATGAGTGGAACACAGAGAATTG
  TGTGGAGTTCCAGAAACTGAATGTGAGCAACTACAGCCATGTGTCTCTGCAGAATGCCAC
  CTCCCCTGTCATGGAGTTTTGGGAGCACCGGGTCCTGGCCATCTCTGACGGGATCGAGCA
  CATCGGGAACCTTCGCTGGGAGCTGGCCTTGTGTCTCTTGGCAGCCTGGACCATCTGTTA
  CTTCTGTATCTGGAAGGGGACCAAGTCTACAGGAAAGGTTGTATACGTGACTGCGACATT
  CCCCTACATCATGCTGCTGATCCTCCTGATACGAGGGGTCACGTTGCCCGGGGCCTCAGA
  GGGCATCAAGTTCTACTTGTACCCTGACCTCTCCCGGCTCTCCGACCCCCAGGTCTGGGT
  AGATGCTGGAACGCAGATCTTTTTCTCCTATGCCATTTGCCTGGGCTGTCTGACCGCTCT
  GGGAAGTTATAACAATTATAACAACAACTGCTACAGGGACTGCATCATGCTCTGTTGCCT
  GAACAGCGGCACCAGCTTCGTGGCTGGGTTTGCCATCTTCTCAGTCCTGGGTTTTATGGC
  GTACGAGCAGGGGGTACCCATTGCTGAGGTGGCAGAGTCAGGCCCCGGCCTGGCCTTTAT
  TGCGTACCCCAAGGCGGTCACCATGATGCCTCTCTCCCCGCTGTGGGCCACCTTGTTCTT
  CATGATGCTCATCTTCCTGGGCCTGGACAGCCAGTTTGTGTGTGTGGAAAGCCTGGTGAC
  CGCCGTGGTGGACATGTACCCCAAGGTTTTCCGGAGGGGTTACCGGCGGGAGCTGCTCAT
  CCTAGCCTTGTCTGTTATCTCCTATTTTCTGGGCCTCGTGATGTTAACAGAGGGTGGCAT
  GTACATCTTCCAGCTCTTTGACTCCTATGCCGCCAGTGGGATGTGCCTTCTCTTCGTGGC
  CATCTTTGAGTGCATCTGCATCGGCTGGGTGTATGGAAGCAACCGGTTCTATGATAACAT
  TGAAGACATGATTGGCTACCGGCCACCGTCGCTCATTAAGTGGTGCTGGATGATCATGAC
  CCCTGGGATCTGCGCGGGGATCTTCATCTTCTTCTTGATCAAGTACAAGCCACTCAAGTA
  CAACAACATCTACACCTACCCAGCCTGGGGCTATGGCATTGGCTGGCTCATGGCCCTGTC
  CTCCATGCTCTGCATCCCGCTCTGGATCTGCATCACAGTGTGGAAGACGGAGGGGACACT
  GCCCGAGAAACTCCAGAAGTTGACGACCCCCAGCACAGATCTGAAAATGCGGGGCAAGCT
  TGGGGTGAGCCCACGGATGGTGACAGTTAATGACTGTGATGCCAAACTCAAGAGTGACGG
  GACCATCGCAGCCATCACAGAGAAGGAGACGCACTTCTGAGCGGCCACCAGCCATCTGGG
  GCTCTTCTTCCTTTCTTCCCCCCGTGTATGTAAATGAATTCCTGAACCCCATACTTCACC
  TAATGGTAGGGGCTTGCTTGTTTTGCACAGGATTAATTAACAAGTTAATTTTAAGGTGGC
  CACTGTACACTGCTCTAAAGTCATATCCCCTCCCCGCCATCGCCGACACACACACACGTC
  GTAATGTGGCTAACGCTTGACTCACTTAACACTACTCATGGGGCAGGGCGGAGGGTGGAT
  TGTTGCTTTTTGTTTTTTGTAATTTCCTACTAGTATTTGGGTAACTTTGGGGGTGGGGAG
  GGCAATGTGGGGGCAGGGGAACATGTCATTGTGATGACTTTTTTGATATTCATTAGAAAC
  AATACATCCTTTTTGAGATATTTACAGTATTATTAAAAAATGAAAAAGGTTGTACTGTTT
  TGCATAATGAACATTTTTATTGGGCATTCAAAGGGTGCAAGATTGTCTGCTTACTCATTT
  TTAAAAATTAAAGAAATGAACAATCAGTGTGGCTATTCCTAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014229 unedited
  ACCGCACCGTTTGAGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGA
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATT
  CGGCACGAGGATGACGGCGGAGAAGGCGCTGCCCCTGGGCAATGGGAAGGCTGCTGAGGA
  GGCGCGGGAGTCCGAGGCGCCGGGTGGCGGCTGCAGCAGCGGGGGCGCGGCGCCCGCGCG
  CCACCCGCGCGTCAAGCGCGACAAGGCGGTCCACGAGCGCGGCCACTGGAACAACAAGGT
  GGAGTTCGTGCTGAGCGTGGCCGGGGAGATCATTGGGCTGGGCAACGTGTGGCGCTTCCC
  CTACCTGTGCTACAAGAACGGAGGAGGGGCATTCCTGATTCCCTACGTGGTGTTTTTTAT
  TTGCTGTGGAATTCCTGTTTTTTTCCTGGAGACAGCTCTGGGGCAGTTCACAAGTGAAGG
  TGGCATTACGTGTTGGAGGAAAGTTTGCCCTTTATTTGAAGGCATTGGCTATGCAACACA
  GGTGATTGAGGCCCATCTGAATGTGTACTACATCATCATCCTGGCATGGGCCATTTTTTA
  CCTGAGCAACTGCTTCACTACTGAGCTACCCTGGGCTACCTGTGGGCATGAGTGGAACAC
  AGAGAATTGTGTGGAGTTCCAGAAACTGAATGTGAGCAACTACAGCCATGTGTCTCTGCA
  GAATGCCACCTCCCCTGTCATGGAGTTTTGGGAGCACCGGGTCCTGGCCATCTCTGACGG
  GATCGAGCACATCGGGAACCTTCGCTGGGAGCTGGCCTTGTGTCTCTTGGCAGCCTGACC
  ATCTGTTACTTCTGTATCTGGAGGGGACCAAGTCTACAGGAAAGGTTGTAATACGTGACT
  GCGACATTTCGTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_014229 unedited
  AGGGGGTGAACCTCGGGCCGGAAAGCACCGGGGAGGGGTCCAGGGATGCCCCCGGGATCT
  GTTCGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGCTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTAGGAATAGCCACACTGATTGTTCATTTCTTTAATTTTTAA
  AAATGAGTAAGCAGACAATCTTGCACCCTTTGAATGCCCAATAAAAATGTTCATTATGCA
  AAACAGTACAACCTTTTTCATTTTTTAATAATACTGTAAATATCTCAAAAAGGATGTATT
  GTTTCTAATGAATATCAAAAAAGTCATCACAATGACATGTTCCCCTGCCCCCACATTGCC
  CTCCCCACCCCCAAAGTTACCCAAATACTAGTAGGAAATTACAAAAAACAAAAAGCAACA
  ATCCACCCTCCGCCCTGCCCCATGAGTAGTGTTAAGTGAGTCAAGCGTTAGCCACATTAC
  GACGTGTGTGTGTGTCGGCGATGGCGGGGAGGGGATATGACTTTAGAGCAGTGTACAGTG
  GCCACCTTAAAATTAACTTGTTAATTAATCCTGTGCAAAACAAGCAAGCCCCTACCATTA
  GGTGAAGTATGGGGTTCAGGAATTCATTTACATACACGGGGGGAAGAAAGGAAGAAGAGC
  CCCAGATGGCTGGTGGCCGCTCAGAAGTGCGTCTCCTTCTCTGTGATGGCTGCGATGGTC
  CCGTCACTCTTGAGTTTGGCATCACAGTCATTAACTGTCACCATCCGTGGGCTCACCCCA
  AGCTTGCCCCCGCATTTTCAGATCTGTGCTGGGGGTCGTCAACTTCTGAGTTTCTCGGCA
  GTGTCCCCTCCGTCTTCCACACTGTGATGCAGATCCAGAGCGGGATGCAGAGCATGAGAC
  AGGCCATGAACCAGCCATGCCATAGCCCAGCTGGTTAGTGTAGATGTTGTTGTACTGATG
  GCTTGTACCTTGATCAGAGAGATGAGATCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_014229
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014229.1, NP_055044.1
• RefSeq Size: 1991 bp
• RefSeq ORF: 1899 bp
• Locus ID: 6538
• UniProt ID: P48066
• Cytogenetics: 3p25.3
• Domains: SNF
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.