SHANK1 (NM_016148) Human Untagged Clone

CAT#: SC304385

SHANK1 (untagged)-Human SH3 and multiple ankyrin repeat domains 1 (SHANK1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SHANK1
• Synonyms: SPANK-1; SSTRIP; synamon
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016148, the custom clone sequence may differ by one or more nucleotides
  ATGACCCACAGCCCCGCGACAAGCGAGGACGAGGAACGCCACAGTGCCAGCGAGTGTCCC
  GAGGGGGGCTCAGAGTCCGACAGCTCCCCAGACGGGCCAGGTCGAGGCCCCCGGGGGACC
  CGGGGCCAGGGCAGTGGGGCACCTGGTAGCCTGGCCTCTGTTAGAGGCCTCCAGGGCCGC
  TCAATGTCCGTCCCAGACGACGCCCACTTCAGCATGATGGTCTTCAGGATTGGCATCCCG
  GACCTGCACCAGACAAAATGCCTTCGCTTCAACCCCGATGCCACCATCTGGACGGCCAAG
  CAGCAGGTGCTCTGTGCCCTGAGCGAGAGCCTGCAGGATGTGCTCAACTATGGCCTGTTC
  CAACCGGCCACCTCCGGCCGCGATGCCAACTTCCTGGAGGAGGAGAGGCTGCTGCGGGAG
  TACCCCCAGTCCTTTGAGAAGGGGGTCCCCTACCTGGAGTTCCGATACAAGACCCGAGTT
  TACAAACAGACCAACCTGGATGAGAAGCAGCTGGCCAAGTTGCACACGAAGACGGGGTTG
  AAGAAGTTCCTGGAGTATGTGCAGCTCGGGACATCTGACAAGGTGGCGCGGCTGCTGGAC
  AAGGGGCTGGACCCCAATTACCATGACTCGGATTCGGGAGAGACCCCCTTGACACTGGCG
  GCCCAGACCGAAGGCTCTGTAGAGGTGATTCGAACCCTGTGCCTGGGCGGGGCCCACATT
  GACTTCCGGGCCCGGGATGGCATGACCGCACTGCATAAGGCCGCATGCGCCCGACACTGC
  CTGGCACTCACGGCGCTCCTGGACCTTGGGGGTTCCCCCAACTACAAGGACCGTCGGGGG
  CTGACCCCTCTGTTCCACACGGCCATGGTGGGTGGTGACCCCCGATGCTGCGAGCTGCTC
  CTGTTCAACAGGGCCCAGCTGGGCATAGCTGATGAGAACGGCTGGCAGGAAATCCACCAG
  GCCTGCCAGCGGGGTCACTCTCAGCACCTGGAGCATCTGCTTTTCTACGGGGCTGAGCCT
  GGAGCCCAGAACGCCTCGGGGAACACGGCTCTGCACATCTGCGCCCTCTACAACAAGGAG
  ACCTGTGCCAGGATCCTCCTGTATCGAGGTGCCGACAAGGATGTGAAGAACAACAACGGA
  CAGACCCCCTTCCAGGTGGCAGTGATTGCTGGGAATTTTGAGCTGGGGGAGCTGATCCGA
  AACCACCGAGAACAGGATGTGGTGCCCTTCCAGGAGTCCCCCAAGTACGCGGCCCGGCGA
  CGGGGGCCCCCAGGCACAGGGCTGACGGTGCCCCCGGCGCTGCTGCGGGCCAACAGTGAC
  ACCAGCATGGCGCTGCCCGACTGGATGGTGTTCTCCGCCCCGGGGGCCGCGTCCTCTGGG
  GCCCCTGGCCCTACCTCAGGGTCCCAGGGCCAGTCGCAGCCCTCGGCCCCCACCACCAAG
  CTCAGCAGCGGGACCCTCCGAAGTGCCAGCAGCCCCCGGGGTGCCAGGGCCCGCTCTCCA
  TCCCGAGGGAGGCACCCTGAGGACGCCAAGAGGCAGCCCCGAGGCCGGCCCAGCTCCAGC
  GGGACACCCCGGGAAGGGCCAGCCGGGGGCACGGGGGGCTCAGGGGGCCCCGGGGGCTCC
  CTGGGCAGCCGCGGGAGGCGGAGGAAGCTCTACTCAGCGGTACCCGGACGCTCCTTCATG
  GCTGTGAAGTCCTACCAGGCCCAAGCCGAGGGGGAGATCTCCCTGAGCAAGGGCGAGAAG
  ATCAAAGTACTTAGCATCGGGGAAGGAGGCTTCTGGGAAGGCCAGGTCAAAGGTCGTGTT
  GGCTGGTTCCCCTCTGACTGCCTGGAAGAAGTGGCGAATCGCTCTCAGGAGAGCAAGCAA
  GAAAGCCGCAGTGACAAGGCAAAGAGACTCTTCCGGCATTATACCGTGGGCTCCTACGAC
  AGCTTTGATGCCCCAAGCTTAATGGATGGGATTGGCCCAGGGAGCGATTACATCATTAAG
  GAGAAGACAGTCTTGCTGCAGAAGAAGGACAGTGAGGGGTTTGGGTTCGTGCTCCGGGGG
  GCCAAGGCGCAGACCCCCATCGAGGAGTTCACCCCCACCCCGGCCTTCCCGGCGCTGCAG
  TACCTGGAGTCGGTGGACGAGGGTGGCGTGGCATGGCGAGCTGGACTGCGAATGGGAGAC
  TTCCTCATCGAGGTGAACGGGCAGAATGTGGTGAAGGTCGGCCACCGACAGGTGGTGAAC
  ATGATCCGCCAAGGGGGCAACACGCTGATGGTGAAGGTGGTGATGGTCACCAGGCACCCG
  GACATGGATGAGGCAGTGCACAAGAAAGCACCCCAGCAGGCCAAGCGGCTGCCGCCCCCA
  ACCATCTCCCTGCGTTCCAAATCTATGACCTCAGAGCTGGAGGAGATGGAGTACGAGCAG
  CAGCCGGCGCCGGTGCCCAGCATGGAGAAAAAGCGGACCGTGTATCAGATGGCTCTCAAC
  AAACTGGACGAAATCCTGGCCGCAGCTCAACAGACCATCAGTGCAAGCGAAAGCCCTGGT
  CCCGGTGGCCTCGCGTCCCTGGGCAAACACCGACCCAAAGGTTTCTTTGCCACTGAGTCG
  AGCTTCGATCCCCACCACCGTGCCCAGCCAAGTTACGAGCGTCCTTCTTTCCTGCCTCCA
  GGACCTGGGTTGATGCTCCGGCAAAAATCTATCGGTGCGGCAGAAGATGACAGACCTTAC
  CTAGCACCCCCAGCCATGAAATTCAGCCGCAGCCTGTCTGTGCCTGGTTCGGAGGACATT
  CCCCCGCCACCCACCACGTCCCCACCGGAGCCTCCCTACAGCACACCTCCAGTCCCCTCC
  TCCTCAGGGCGCCTCACCCCCTCCCCTCGGGGAGGGCCCTTCAACCCTGGCTCTGGTGGC
  CCCCTCCCCGCCTCCTCCCCTGCATCCTTTGACGGGCCCTCCCCTCCCGACACTCGCGTG
  GGGAGCCGCGAGAAGAGCCTGTACCACAGTGGGCCCCTGCCCCCGGCCCACCACCACCCG
  CCCCACCACCACCACCACCACGCCCCGCCCCCTCAGCCCCACCACCACCACGCCCACCCC
  CCTCATCCTCCCGAGATGGAGACAGGCGGCTCTCCCGACGACCCTCCACCCCGCCTGGCT
  CTGGGGCCCCAGCCCAGCCTGCGAGGCTGGAGGGGCGGCGGGCCCAGCCCGACCCCGGGG
  GCCCCGTCCCCATCGCACCACGGCAGCGCGGGCGGGGGCGGCGGCTCCTCCCAGGGCCCG
  GCTCTACGCTATTTCCAGCTGCCCCCGCGGGCGGCCAGCGCAGCCATGTACGTGCCCGCC
  CGCTCGGGCCGCGGCCGCAAGGGCCCGCTGGTCAAGCAGACCAAGGTGGAAGGCGAGCCC
  CAGAAGGGCGGCGGCCTCCCGCCCGCGCCGTCGCCCACGTCCCCGGCCTCCCCGCAGCCG
  CCGCCCGCCGTGGCCGCGCCCTCGGAGAAGAACTCCATCCCCATCCCCACCATCATCATC
  AAGGCCCCGTCCACCAGTAGCAGCGGCCGCAGCAGCCAGGGCAGCAGCACCGAGGCGGAG
  CCCCCCACCCAGCCGGAGCCCACGGGAGGCGGCGGCGGCGGCGGCTCCTCGCCCAGCCCC
  GCCCCGGCCATGTCACCCGTGCCCCCGTCCCCCTCGCCCGTGCCCACCCCCGCCTCGCCC
  AGCGGCCCGGCCACGCTGGACTTCACGAGCCAGTTCGGGGCCGCCCTGGTGGGGGCGGCC
  CGGAGGGAGGGGGGCTGGCAGAATGAGGCGCGCCGGCGCTCCACGCTGTTCCTGTCCACC
  GACGCGGGGGACGAGGACGGCGGGGACGGCGGGCTGGGCACAGGGGCGGCCCCGGGCCCG
  CGGCTGCGCCACTCCAAATCCATCGACGAGGGCATGTTCTCCGCCGAGCCCTACCTCCGA
  CTGGAGTCTGCGGGCAGCGGCGCGGGCTACGGCGGCTACGGGGCCGGTAGCCGAGCCTAC
  GGGGGTGGCGGGGGCAGCAGCGCCTTCACCAGCTTCCTGCCCCCGCGACCCCTGGTGCAC
  CCGCTGACCGGCAAGGCCCTGGATCCCGCCTCCCCGCTGGGGCTGGCCCTGGCCGCCCGC
  GAGCGAGCGCTGAAGGAGTCCTCGGAGGGCGGCGGGGCCCCCCAGCCGCCTCCCAGGCCC
  CCATCGCCCCGCTACGAGGCCCCGCCGCCCACCCCGCACCACCACTCGCCCCACGCCCAC
  CACGAGCCAGTGCTGCGTCTCTGGGGGGCCTCCCCGCCGGACCCTGCGCGCCGGGAGCTG
  GGGTACAGGGCCGGGCTGGGCAGCCAGGAGAAGTCCCTTCCCGCCAGCCCGCCCGCCGCC
  CGGCGTTCCCTGCTACACCGCCTGCCGCCCACCGCTCCCGGGGTGGGGCCCCTCCTGCTG
  CAGCTGGGGACGGAGCCCCCGGCCCCGCACCCCGGAGTAAGCAAGCCCTGGAGGTCCGCA
  GCCCCCGAAGAACCCGAGCGGCTGCCGCTGCACGTGCGGTTCCTTGAAAACTGCCAGCCC
  CGGGCCCCTGTGACGAGCGGAAGGGGTCCCCCCTCGGAGGACGGGCCGGGGGTCCCGCCG
  CCCAGCCCACGCCGGTCCGTGCCCCCCTCCCCGACCTCCCCGAGGGCCAGCGAAGAGAAC
  GGGCTGCCCCTGCTGGTCCTGCCGCCTCCCGCCCCCTCGGTGGATGTGGAAGATGGCGAA
  TTCCTTTTCGTGGAACCGCTGCCTCCGCCTCTGGAATTCTCCAACAGCTTCGAAAAGCCA
  GAGTCGCCCCTCACGCCTGGGCCTCCCCACCCGCTGCCCGACACACCTGCCCCTGCCACC
  CCGTTACCCCCTGTGCCACCCCCGGCTGTGGCCGCAGCCCCTCCCACCCTGGACTCCACC
  GCATCCAGCCTGACATCCTATGACAGCGAGGTGGCCACCCTGACCCAGGGGGCCTCCGCC
  GCTCCTGGGGACCCCCATCCACCAGGCCCGCCTGCCCCAGCAGCACCGGCTCCCGCTGCC
  CCACAGCCTGGCCCGGACCCTCCGCCTGGCACGGATTCTGGCATCGAGGAGGTGGACAGT
  CGGAGCAGCAGTGACCACCCACTGGAGACCATCAGCAGCGCCTCCACGCTGAGCAGCCTA
  TCTGCCGAAGGTGGTGGCAGCGCAGGGGGTGGGGGCGGGGCTGGGGCCGGTGTGGCCAGT
  GGGCCGGAGCTTCTGGACACCTATGTGGCCTACCTGGACGGCCAGGCCTTTGGGGGCAGC
  AGTACTCCCGGCCCGCCATACCCTCCTCAGCTCATGACTCCCTCTAAGCTCCGGGGCCGG
  GCGCTAGGAGCCAGCGGAGGCCTGCGGCCTGGCCCCAGCGGGGGACTCCGAGACCCTGTT
  ACCCCCACCAGCCCCACCGTCTCGGTGACAGGGGCTGGAACCGATGGGCTGCTGGCCCTG
  CGTGCTTGTTCAGGACCCCCCACGGCAGGCGTGGCGGGGGGTCCGGTGGCTGTAGAGCCA
  GAAGTCCCACCGGTGCCCTTGCCGACGGCCTCCTCTCTGCCCCGGAAGCTGCTGCCCTGG
  GAGGAGGGCCCGGGCCCACCGCCACCACCTCTGCCCGGGCCCTTGGCCCAGCCTCAGGCC
  TCAGCCTTGGCCACAGTAAAAGCCAGCATCATCAGTGAACTCAGCTCCAAGCTTCAGCAG
  TTTGGGGGCTCCTCGGCAGCTGGCGGCGCTCTGCCCTGGGCCCGAGGAGGCAGTGGGGGA
  GGCGGAGACAGCCACCACGGGGGAGCCAGCTATGTCCCCGAGAGGACCTCCTCCCTGCAG
  CGGCAGAGACTCTCCGACGACTCCCAGTCCTCACTCCTCTCCAAGCCTGTCAGCAGCCTG
  TTTCAGAACTGGCCCAAACCACCTCTGCCGCCACTCCCCACCGGAACAGGGGTCTCCCCT
  ACAGCCGCTGCGGCCCCAGGGGCCACCTCACCCTCAGCCTCCTCCTCCTCCACGTCCACC
  CGCCACCTCCAGGGCGTGGAGTTCGAGATGCGGCCCCCTCTGCTCCGCCGGGCCCCCAGC
  CCCTCGCTGCTGCCCGCCTCGGAGCACAAGGTCAGCCCTGCGCCCAGGCCCTCGTCCCTG
  CCCATCCTGCCTTCCGGACCCCTCTACCCAGGCCTCTTTGACATCCGTGGCTCCCCAACT
  GGAGGGGCAGGAGGCTCGGCTGACCCCTTCGCCCCAGTCTTTGTGCCGCCACACCCGGGG
  ATATCCGGGGGGCTCGGGGGAGCCTTGTCAGGGGCCTCGCGCTCCCTCTCACCGACCCGC
  CTGCTCTCGCTGCCCCCGGACAAGCCGTTTGGCGCTAAACCTCTGGGGTTCTGGACCAAG
  TTCGACGTGGCTGATTGGCTGGAGTGGCTGGGTTTGGCGGAGCACCGAGCCCAGTTCCTG
  GACCACGAGATCGATGGCTCCCACCTGCCCGCCTTGACCAAGGAGGACTACGTCGATCTA
  GGTGTGACCAGGGTGGGCCACCGCATGAACATCGACCGGGCTCTCAAATTCTTCCTGGAG
  AGGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_016148
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016148.1, NP_057232.1
• RefSeq Size: 6643 bp
• RefSeq ORF: 6486 bp
• Locus ID: 50944
• UniProt ID: Q9Y566
• Cytogenetics: 19q13.33
• Gene Summary: This gene encodes a member of the SHANK (SH3 domain and ankyrin repeat containing) family of proteins. Members of this family act as scaffold proteins that are required for the development and function of neuronal synapses. Deletions in this gene may be associated with autism spectrum disorder in males. [provided by RefSeq, Apr 2016]