SHANK1 Rabbit Polyclonal Antibody

CAT#: TA350836

Rabbit Polyclonal Anti-SHANK1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Mouse brain tissue Primary antibody: TA350836 (SHANK1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SHANK1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 225 kDa
• Gene Name: SH3 and multiple ankyrin repeat domains 1
• Database Link:
  NP_057232
  Entrez Gene 78957 RatEntrez Gene 243961 MouseEntrez Gene 50944 Human
  UniProt ID Q9Y566
• Background: SHANK1 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
• Synonyms: SPANK-1; SSTRIP; synamon