Melatonin Related Receptor(GPR50) (NM_004224) Human Tagged ORF Clone

CAT#: RG217839

GPR50 (GFP-tagged) - Human G protein-coupled receptor 50 (GPR50)

  • TrueORF®

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Size
    • 10 ug

Cited in 1 publication.

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Specifications

Product Data
Product Name Melatonin Related Receptor(GPR50) (NM_004224) Human Tagged ORF Clone
Symbol GPR50
Synonyms H9; Mel1c
Vector pCMV6-AC-GFP
Sequence Data
>RG217839 representing NM_004224
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGGCCCACCCTAGCGGTTCCCACCCCCTATGGCTGTATTGGCTGTAAGCTACCCCAGCCAGAATACC
CACCGGCTCTAATCATCTTTATGTTCTGCGCGATGGTTATCACCATCGTTGTAGACCTAATCGGCAACTC
CATGGTCATTTTGGCTGTGACGAAGAACAAGAAGCTCCGGAATTCTGGCAACATCTTCGTGGTCAGTCTC
TCTGTGGCCGATATGCTGGTGGCCATCTACCCATACCCTTTGATGCTGCATGCCATGTCCATTGGGGGCT
GGGATCTGAGCCAGTTACAGTGCCAGATGGTCGGGTTCATCACAGGGCTGAGTGTGGTCGGCTCCATCTT
CAACATCGTGGCAATCGCTATCAACCGTTACTGCTACATCTGCCACAGCCTCCAGTACGAACGGATCTTC
AGTGTGCGCAATACCTGCATCTACCTGGTCATCACCTGGATCATGACCGTCCTGGCTGTCCTGCCCAACA
TGTACATTGGCACCATCGAGTACGATCCTCGCACCTACACCTGCATCTTCAACTATCTGAACAACCCTGT
CTTCACTGTTACCATCGTCTGCATCCACTTCGTCCTCCCTCTCCTCATCGTGGGTTTCTGCTACGTGAGG
ATCTGGACCAAAGTGCTGGCGGCCCGTGACCCTGCAGGGCAGAATCCTGACAACCAACTTGCTGAGGTTC
GCAATTTTCTAACCATGTTTGTGATCTTCCTCCTCTTTGCAGTGTGCTGGTGCCCTATCAACGTGCTCAC
TGTCTTGGTGGCTGTCAGTCCGAAGGAGATGGCAGGCAAGATCCCCAACTGGCTTTATCTTGCAGCCTAC
TTCATAGCCTACTTCAACAGCTGCCTCAACGCTGTGATCTACGGGCTCCTCAATGAGAATTTCCGAAGAG
AATACTGGACCATCTTCCATGCTATGCGGCACCCTATCATATTCTTCTCTGGCCTCATCAGTGATATTCG
TGAGATGCAGGAGGCCCGTACCCTGGCCCGCGCCCGTGCCCATGCTCGCGACCAAGCTCGTGAACAAGAC
CGTGCCCATGCCTGTCCTGCTGTGGAGGAAACCCCGATGAATGTCCGGAATGTTCCATTACCTGGTGATG
CTGCAGCTGGCCACCCCGACCGTGCCTCTGGCCACCCTAAGCCCCATTCCAGATCCTCCTCTGCCTATCG
CAAATCTGCCTCTACCCACCACAAGTCTGTCTTTAGCCACTCCAAGGCTGCCTCTGGTCACCTCAAGCCT
GTCTCTGGCCACTCCAAGCCTGCCTCTGGTCACCCCAAGTCTGCCACTGTCTACCCTAAGCCTGCCTCTG
TCCATTTCAAGGCTGACTCTGTCCATTTCAAGGGTGACTCTGTCCATTTCAAGCCTGACTCTGTTCATTT
CAAGCCTGCTTCCAGCAACCCCAAGCCCATCACTGGCCACCATGTCTCTGCTGGCAGCCACTCCAAGTCT
GCCTTCAGTGCTGCCACCAGCCACCCTAAACCCACCACTGGCCACATCAAGCCAGCTACCAGCCATGCTG
AGCCCACCACTGCTGACTATCCCAAGCCTGCCACTACCAGCCACCCTAAGCCCACTGCTGCTGACAACCC
TGAGCTCTCTGCCTCCCATTGCCCCGAGATCCCTGCCATTGCCCACCCTGTGTCTGACGACAGTGACCTC
CCTGAGTCGGCCTCTAGCCCTGCCGCTGGGCCCACCAAGCCTGCTGCCAGCCAGCTGGAGTCTGACACCA
TCGCTGACCTTCCTGACCCTACTGTAGTCACTACCAGTACCAATGATTACCATGATGTCGTGGTTGTTGA
TGTTGAAGATGATCCTGATGAAATGGCTGTG


ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
>RG217839 representing NM_004224
Red=Cloning site Green=Tags(s)

MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSL
SVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIF
SVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVR
IWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAY
FIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQD
RAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP
VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKS
AFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDL
PESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVVDVEDDPDEMAV

TRTRRLE - GFP Tag - V
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
Tag TurboGFP
ACCN NM_004224
ORF Size 1851 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_004224.2, NP_004215
RefSeq Size 2010
RefSeq ORF 1854
Locus ID 9248
Cytogenetics Xq28
Protein Families GPCR, Transmembrane, Druggable Genome
Protein Pathways Neuroactive ligand-receptor interaction
Gene Summary This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)