GPR179 (NM_001004334) Human Tagged ORF Clone

CAT#: RC224221

GPR179 (Myc-DDK-tagged)-Human G protein-coupled receptor 179 (GPR179)

Product Images

Circular map for RC224221

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: GPR179
• Synonyms: CSNB1E; GPR158L; GPR158L1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC224221 representing NM_001004334
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCACCAGGGGAGCGGTCATGCCCCCTCCTATGTGGGGGCTGCTGGGCTGCTGTTTTGTCTGTGCCT
  GGGCTCTGGGGGGTCCACGGCCCATCCGCTCTCTGCCCCCTCTGTCTTCCCAAGTCAAGCCAGGATCTGT
  ACCCATGCAGGTGCCCCTAGAGGGGGCCGAGGCCGCCCTCGCTTATCTCTACTCTGGAGATGCCCAGCAG
  CTATCACAGGTGAATTGCAGTGAGCGCTATGAAGCGCGTGGGGCAGGAGCCATGCCAGGGCTCCCCCCAA
  GCCTACAGGGGGCAGCGGGCACCCTTGCCCAGGCCGCCAATTTTCTCAACATGCTGCTGCAAGCCAACGA
  CATCCGTGAGTCCAGTGTGGAGGAGGATGTGGAATGGTACCAGGCACTGGTCCGCAGCGTGGCCGAGGGG
  GACCCAAGAGTGTACAGGGCTTTGCTGACCTTTAACCCTCCACCAGGGGCCAGCCACCTACAGCTGGCCC
  TGCAGGCCACCCGGACTGGGGAGGAAACCATCCTGCAGGACTTGTCTGGGAACTGGGTGCAGGAGGAGAA
  CCCTCCTGGGGACCTGGACACCCCTGCCCTGAAGAAGCGAGTGTTGACCAATGACCTAGGGAGCCTCGGC
  AGCCCCAAGTGGCCGCAGGCAGATGGATATGTGGGGGACACGCAGCAGGTGAGGCTGTCTCCTCCTTTCC
  TGGAATGCCAGGAGGGACGGCTCCGACCTGGATGGCTGATCACACTCTCTGCCACCTTCTATGGACTCAA
  GCCAGACCTCAGCCCAGAAGTCAGGGGGCAGGTGCAGATGGACGTAGATCTCCAGAGTGTGGACATCAAT
  CAGTGTGCAAGTGGCCCAGGCTGGTACTCTAACACACACCTGTGTGATCTCAACAGCACCCAGTGTGTTC
  CCCTGGAGAGTCAGGGCTTTGTTCTTGGCCGCTACCTCTGCCGCTGCCGACCTGGATTCTACGGGGCAAG
  CCCCTCTGGGGGGTTAGAGGAGAGTGACTTCCAGACTACCGGGCAATTCGGGTTCCCAGAAGGCAGATCT
  GGGAGACTGCTGCAGTGTCTGCCATGTCCTGAGGGCTGCACCAGCTGCATGGATGCCACACCGTGCCTGG
  TGGAAGAGGCCGCGGTGCTGCGGGCCGCTGTGCTGGCCTGCCAGGCCTGCTGCATGCTGGCCATCTTCCT
  GAGCATGCTGGTCTCCTACCGCTGCCGCCGGAACAAGAGGATCTGGGCATCTGGAGTGGTCCTGCTGGAA
  ACTGTCCTTTTTGGATTCCTGCTGCTTTACTTTCCTGTCTTCATCCTATACTTCAAGCCCAGTGTATTCC
  GCTGCATCGCTCTTCGCTGGGTGCGGCTGCTGGGTTTTGCCATCGTCTACGGCACCATCATACTCAAGCT
  TTACAGAGTGCTGCAGCTGTTTCTGTCTCGAACGGCCCAGCGGAGTGCCCTTCTGAGCAGCGGGCGGCTG
  CTGCGGCGCCTGGGGCTGCTCCTGCTACCTGTGCTGGGCTTCCTGGCTGTGTGGACCGTGGGCGCCCTGG
  AGCGAGGCATCCAGCACGCACCTCTGGTGATCCGAGGCCACACTCCCAGTGGCCGCCATTTCTACCTCTG
  TCACCACGACCGCTGGGACTACATCATGGTTGTGGCTGAGCTGCTGCTGCTGTGCTGGGGCAGCTTCCTC
  TGCTACGCCACACGGGCTGTGCTCTCGGCCTTCCATGAGCCACGCTACATGGGCATCGCCCTGCACAATG
  AGCTACTGCTTTCCGCTGCCTTCCACACAGCCAGGTTTGTGCTGGTTCCCTCTCTGCACCCGGACTGGAC
  CCTCCTCCTCTTCTTCTTCCACACCCACAGCACAGTCACCACCACGCTGGCTCTGATCTTCATCCCTAAG
  TTCTGGAAGCTGGGGGCTCCTCCCCGGGAGGAGATGGTGGATGAGGTGTGTGAGGACGAGCTGGACCTGC
  AGCACTCAGGCTCCTACCTTGGCAGCAGCATCGCCTCAGCCTGGAGTGAGCACAGCCTGGACCCTGGAGA
  CATTCGGGACGAGCTGAAGAAGCTCTATGCCCAGCTAGAGGTCCACAAAACCAAGGAAATGGCCGCAAAC
  AACCCCCACCTGCCCAAGAAGCGAGGCAGCTCATGCCAGGGACTGGGCCGCTCCTTCATGAGGTACCTGG
  CGGAATTCCCCGAGGCCCTGGCCAGGCAGCACTCCCGGGACTCAGGATCCCCAGGCCACGGCAGCCTGCC
  CGGCTCCTCCCGCCGCCGGCTCCTCAGCTCCAGCCTCCAGGAACCCGAGGGGACACCAGCTCTGCACAAG
  TCCCGCAGCACCTATGACCAGCGCAGGGAGCAGGACCCGCCTCTTCTTGACTCACTGCTGAGGAGGAAGC
  TGGCCAAGAAGGCCTCTCGAACAGAGAGCCGGGAGTCGGTGGAGGGGCCCCCTGCCCTGGGCTTCAGGTC
  AGCCAGCGCCCACAACCTGACGGTGGGAGAGAGGCTACCCAGAGCCCGGCCCGCCTCTCTGCAGAAGTCG
  CTCAGTGTGGCCAGCTCCAGGGAAAAGGCCTTGCTCATGGCCAGCCAGGCCTACCTGGAGGAGACCTACC
  GGCAAGCAAAGGAGCGGGAGGAGCGGAAGAAGGCCAAGGCAGCCATGGCCAGCCTGGTGCGGAGGCCATC
  AGCCAGGAGGCTGGAGCGGCCTCGAGGGGCCCCCCTGTCAGCTCCACCTTCCCCTGCCAAGAGCAGCAGC
  GTGGACAGCTCTCACACCTCTGGGAGGCTTCATGAGGAGGCTAGGAGAAGGCTGCCTCATCCACCCATCA
  GGCACCAGGTTTCTACCCCCATCTTGGCCCTGTCTGGGGGCCTGGGAGAGCCAAGGATGCTATCTCCCAC
  CTCCACCTTGGCTCCAGCTCTGCTGCCAGCTCTAGCTCCAACCCCAGCCCCTGCCCTGGCACCAGTCCCA
  GTATCCCCACAAAGCCCCAACTTACTCACCTACATCTGCCCCTGGGAGAACGCAGAACTGCCAGCCAAGC
  AAGAAAATGTGCCCCAGGAAGGCCCCTCAGGGCCAGAGCGAGGCCACCACTCCCCTGCCCCAGCTCGAGC
  CAGGCTCTGGAGGGCCCTCTCTGTTGCAGTAGAGAAAAGCAGGGCTGGGGAGAATGAGATGGACGCAGAG
  GATGCACATCACCAGAGGGAAGCTAATGATGTGGACGAAGACAGGCCCAAGATCTTCCCTAAATCCCACA
  GCCTCAAGGCCCCTGTTCAGCAGGGTTCCATGCGCAGCCTGGGGCTGGCGATTAAAGCTCTGACCCGTTC
  TCGGAGCACCTACAGAGAGAAGGAGAGTGTGGAGGAGAGTCCCGAGGGGCAGAACAGCGGGACTGCGGGA
  GAGAGTATGGGGGCACCCTCCCGATCGCCCAGGCTAGGCCGGCCCAAGGCGGTGAGTAAGCAGGCCGCTC
  TTATCCCCTCCGATGACAAGGAGTCCCTCCAGAACCAACAGAACGCTCACACCAGCAGGATGCTCCAAGT
  CTGTCAACGGGAGGGCAGCAGGGAACAAGAAGACAGAGGCAGGAGGATGACCCAGGGTCTAGGGGAACGG
  AAAGCTGAGAGAGCAGGTAAAACAGGGCTTGCCATGCTGAGGCAAGTTTCCAGGGACAAAAACATCAAGC
  AATCAAAAGAAACCCCTGTCGGGTGGCAGGAACTGCCCAAAGCTGGCCTCCAGTCCCTCGGCAGCGCTGA
  CCACAGGGTGGCAGAGGTATGCCCCTGGGAGGTCACTGAATCAGAAACGCGTCAGCCAGACAGTGGCAAC
  AAGGCCGAAATCTGCCCCTGGGAGACGAGTGAAGGAGCCCCAGAGTCGAGGGCACTAAGACAAGACCCAG
  GTGACTCCCAAAAAAAGAGAGGGGAGGCCCGGGGAAAATCAGAGCCCATAGATGTGGTTCCCATGATGCG
  GAAAAAGCCAGAGAGGCTGGTGAGGGAGCAGGAAGCAGTGTGTCCCTGGGAGAGTGCCGATCGAGGAGGT
  CTGTCCCCTGGGTCAGCTCCTCAGGACCCTGGCAGAATCAGAGACAAATCTGAGGCGGGGGACAGTGTGG
  AGGCCAGGAAGGTGGAGAAGCCTGGGTGGGAAGCTGCTGGCCCAGAAGCTCATACCCCTGACATCACCAA
  GGCAGAGCCGTGTCCCTGGGAGGCAAGTGAAGGAGGCGAGGATGGGAAACCAGCCCAAGAGGCAGTGAAG
  GATCTCCCTCAGGAAAAGCAGAAAACCAGGAAAGCAACCTTTTGGAAAGAACAGAAACCGGGAGGAGACT
  TGGAGTCTCTTTGTCCATGGGAGAGTACAGATTTCCGGGGCCCCTCAGCAGTCTCAATTCAGGCCCCAGG
  AAGCTCAGAGTGTTCAGGGAGTTTGGGCAGTGGCATTGCTGAAGTGTGTCTGTGGGAGGCAGGAGATGCT
  CCTGCTATCCAGAAAGCAGAGATCTGTCCCTGGGAGCTGGATGATAACGTGATGGGGCAGGAAATGCTGA
  GTCTGGGGACAGGTAGAGAATCTCTTCAAGAAAAGGAAAAAGCCTCCAGAAAAGGAAGCTTTGGAGAGAT
  GGGGGAACAAACTGTGAAAGCAGTGCAGAAATTAAGTCAACAGCAGGAGTCAGTTTGTCCCAGGGAGAGC
  ACGGTCCCTGGGCACTCCAGCCCATGTCTAGACAATTCCTCATCCAAAGCTGGTAGCCAATTCCTATGCA
  ATGGAGGAAGCAGAGCAACGCAGGTGTGTCCACAGGAAGATCTCAGGCCGGAGGCACAGGAAGCAACACC
  TGCCAAAACAGAAATCTGTCCCTGGGAGGTAAATGAAAGAACAAGAGAGGAATGGACATCAGCACAGGTG
  CCAAGAGGAGGAGAATCTCAAAAGGACAAGGAGAAAATGCCTGGAAAATCGGAAATCGAAGATGTCACAG
  CTTGGGAAAAGCCTGAGGGGCAGATCCAAAAGCAAGAAGCGGTCGGCCCCTGGGAGAGTGTGGACCCTGG
  CAGCTTCTCCCCACAACCACGTCCTCAAGACACAGAGAGACCCCAAACCCTTCTCCAGATGTCAGGCAGT
  GTGGGAAGCAAAGCTGCCGACATTTGCCCTTTGGATGTGGAGGAAAACTTGACTGCTGGGAAGGCAGAAA
  TCTGTCCCTGGGAGGTGGGTGCTGGAGCAGGGGAGGAAAGGGCTTTGGGAGCTGAGGCCATTAGGAAATC
  TCCAAATGATACAGGCAAGGTTTCTGCAGATCTTGGACCCAGGGAGAGAGCTGTTACTGCTCCAGAGAAG
  CCACAGAAGCCAACCCCAGAGTGGGAGGTGGCTTGTCCCTGGGGGAGTGTGGGTCCAGGGGCCTGTTCTC
  AGCATCCAGGTACTCTAGATGCTGATGGACCAAAAGCTGGGTTCCAGGAACTGGATCATATGGGCTGCAG
  GCCAGGTGAAGTGTGTCCCTGGGAAGCACAGGAAGCTGCTACCAGTGAAAAAGCCAAGATCTGTCCCTGG
  GAGGTAAGTGAAGGAACTACTGGGAAGGGATTGGACCAAAAGGCAGGGAGTGAATCAGCAGAGCAGAGGG
  AGAAAGCTCTAGAAAAGGGGAGACTCACTTCCCTGGGAGAAGACGTATCAAAAGGGATGGCAAAACTGTG
  TCAACAACAGGAAACTATTTGTATTTGGGAGAACAAGGACTTGAGGGAATCCCCTGCTCAGGCCCCCAAG
  ATCTCAGACTTGCCCAGCAGCATGAGTAGTGAAGTGGCAGAGGGACATTCCTTGGAAGCAACAGAGAAGG
  GGGACCTGAGACAAGACCCAAAGACAGGTTCCTTCCCAGAACACATAACCCAAGAAAAAGCTCCAGCTGC
  AGACACAGAAGAATTCACTACTGAAGATGGGGAAAAAACAAGCCATGAGCTACAATCCGTCTGTCCATGG
  GAGACCACTGCCCCAGCAGATTCCGTCTCTCACCTAGACAGACAGCGCCCTGACCAACCTAAAGCTAGCT
  CCCAGAGACTGGTCAGCACTGGGGGCAGGGCCGCTGACGTGTGCCCATGGGATGTTCCTGATGCAGGTGT
  GTATAAATCTGACAGCAGTGCCAAGGCTGAGACCTGTCCCTGGGAAGTGACTGAAAGAATCCCTGTCAAA
  GGGGTGTCAAGGCAGGATGGAAAAGGGGACTCTCAAGAAGAGAAAGGCAGAGCCCCAGAAAAATCAGAGC
  CAAAAGGTGTGCCAGTTCAGAAAAAGCCAGAGATGGCAGACTTCAGGCAGCAGGAGGCTGTGTGTCCCTG
  GGAGAGTCAAGATGGCAAGGGTCTGTCCCCACAGCCAGCCCCAGATGCTTCTGACAGAAGCAGAGGCAGT
  TCTGAGGCAGCAGGCAGTGTGGAGACCAGGGTAGCGGAAGTGTGTCTGTGGGAAGTGGTAGAGGCTCCCT
  CTGCCAAGAAAGCAGAGATCTGCCCTTGGGAGGCGGGTGGAGGAGCAGCAGAGGAAGGGGAACAGGAAAG
  AGAATCACAAGGGCAAGGAGAGATGTTCCTTCAGAAGGCAGGACCTGGAGGGACGGAAGAACACTTCTCA
  AAAGCAGCAGCAAAGCCCAGAGAGCAGGAGGCAGTCTGCCCTGGGGAAGGCACAGGCTCAGGAGGGCTCT
  TGCCCCAGTCAGGTGCCCTGGACCCAGAACTCAAAGTCAGCCCCAAGGAAGCAGGCAGCATGGGAAGCAG
  GATGGCAGAGCTGTGCCAATGGGAAATCACAGATCCAGAAGGAAATAAAATAAAGGGTACCATGGCAGAC
  ATCTGTCCTGGGGAGGAAACTGGAGTCCCATCTGAGGAATCTGGCCTCCTGGCTTTAACAGCAACTCGGA
  GAGAATTTTTCCCCACAGCTCCTGAAAAACCACTATGCCTTTTAGTCCATGGGCCTCTGGATCACTTCTT
  TCCAGAAAGCAAAATCCCCTGCCCCAAGGTAAGCAGGCCAGCCAGTACTTTCACTCTAGAAGGTGTCAGA
  GAACTACAAGGACCTTCAGGGCTTGAGCCAAGGACCAGCTTAGCCCCAGAGCCAAGTCTCCAGGAAGCTG
  AGTCTCAGTCTTCGTCCTTAACTGAAGACTCAGGCCAAGTGGCTTTTGAAGCTCAGTATGAAGAATTCAC
  CCCTCCCACTGTCTATCCTTGGGATTGGGAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC224221 representing NM_001004334
  Red=Cloning site Green=Tags(s)
  
  MGTRGAVMPPPMWGLLGCCFVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAALAYLYSGDAQQ
  LSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEG
  DPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSGNWVQEENPPGDLDTPALKKRVLTNDLGSLG
  SPKWPQADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPEVRGQVQMDVDLQSVDIN
  QCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASPSGGLEESDFQTTGQFGFPEGRS
  GRLLQCLPCPEGCTSCMDATPCLVEEAAVLRAAVLACQACCMLAIFLSMLVSYRCRRNKRIWASGVVLLE
  TVLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKLYRVLQLFLSRTAQRSALLSSGRL
  LRRLGLLLLPVLGFLAVWTVGALERGIQHAPLVIRGHTPSGRHFYLCHHDRWDYIMVVAELLLLCWGSFL
  CYATRAVLSAFHEPRYMGIALHNELLLSAAFHTARFVLVPSLHPDWTLLLFFFHTHSTVTTTLALIFIPK
  FWKLGAPPREEMVDEVCEDELDLQHSGSYLGSSIASAWSEHSLDPGDIRDELKKLYAQLEVHKTKEMAAN
  NPHLPKKRGSSCQGLGRSFMRYLAEFPEALARQHSRDSGSPGHGSLPGSSRRRLLSSSLQEPEGTPALHK
  SRSTYDQRREQDPPLLDSLLRRKLAKKASRTESRESVEGPPALGFRSASAHNLTVGERLPRARPASLQKS
  LSVASSREKALLMASQAYLEETYRQAKEREERKKAKAAMASLVRRPSARRLERPRGAPLSAPPSPAKSSS
  VDSSHTSGRLHEEARRRLPHPPIRHQVSTPILALSGGLGEPRMLSPTSTLAPALLPALAPTPAPALAPVP
  VSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALSVAVEKSRAGENEMDAE
  DAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSGTAG
  ESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQNAHTSRMLQVCQREGSREQEDRGRRMTQGLGER
  KAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSADHRVAEVCPWEVTESETRQPDSGN
  KAEICPWETSEGAPESRALRQDPGDSQKKRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGG
  LSPGSAPQDPGRIRDKSEAGDSVEARKVEKPGWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVK
  DLPQEKQKTRKATFWKEQKPGGDLESLCPWESTDFRGPSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDA
  PAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKEKASRKGSFGEMGEQTVKAVQKLSQQQESVCPRES
  TVPGHSSPCLDNSSSKAGSQFLCNGGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQV
  PRGGESQKDKEKMPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRPQDTERPQTLLQMSGS
  VGSKAADICPLDVEENLTAGKAEICPWEVGAGAGEERALGAEAIRKSPNDTGKVSADLGPRERAVTAPEK
  PQKPTPEWEVACPWGSVGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPW
  EVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPK
  ISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKTSHELQSVCPW
  ETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWDVPDAGVYKSDSSAKAETCPWEVTERIPVK
  GVSRQDGKGDSQEEKGRAPEKSEPKGVPVQKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGS
  SEAAGSVETRVAEVCLWEVVEAPSAKKAEICPWEAGGGAAEEGEQERESQGQGEMFLQKAGPGGTEEHFS
  KAAAKPREQEAVCPGEGTGSGGLLPQSGALDPELKVSPKEAGSMGSRMAELCQWEITDPEGNKIKGTMAD
  ICPGEETGVPSEESGLLALTATRREFFPTAPEKPLCLLVHGPLDHFFPESKIPCPKVSRPASTFTLEGVR
  ELQGPSGLEPRTSLAPEPSLQEAESQSSSLTEDSGQVAFEAQYEEFTPPTVYPWDWE
  
  SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001004334
• ORF Size: 7101 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001004334.2
• RefSeq Size: 7980 bp
• RefSeq ORF: 7104 bp
• Locus ID: 440435
• UniProt ID: Q6PRD1
• Cytogenetics: 17q12
• Protein Families: Druggable Genome, Transmembrane
• MW: 257.2 kDa
• Gene Summary: This gene encodes a member of the glutamate receptor subfamily of G protein-coupled receptors. The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. [provided by RefSeq, Apr 2012]