GSDMC (NM_031415) Human Tagged ORF Clone

CAT#: RC223817

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GSDMC (Myc-DDK-tagged)-Human gasdermin C (GSDMC)



  "NM_031415" in other vectors (6)

Special Offer: 20% off the control vector (empty cloning vector without insert). Use code "Shuttle20".

USD 544.00


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Size
    • 10 ug


Product images

Specifications

Product Data
Type Human Tagged ORF Clone
Tag Myc-DDK
Symbol GSDMC
Synonyms MLZE
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RC223817 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCCTCCATGTTGGAACGCATTAGCAAAAATTTGGTCAAAGAGATTGGAAGCAAAGACCTGACATCTG
TCAAATACCTATTGAGTGCCACCAAATTACGTCAGTTTGTTATATTACGAAAGAAGAAGGATTCTCGTTC
ATCATTTTGGGAACAATCTGACTATGTTCCAGTTGAATTCTCCCTCAATGACATCCTGGAGCCAAGTTCT
TCAGTCCTAGAAACTGTTGTGACAGGACCGTTCCACTTCAGTGACATTATGATCCAGAAGCATAAGGCTG
ACATGGGTGTGAATGTTGGTATAGAAGTGAGTGTGTCAGGGGAGGCCTCTGTGGACCATGGATGCTCCCT
CGAGTTTCAAATTGTTACCATCCCATCACCAAACCTGGAAGACTTTCAAAAAAGGAAACTGTTGGATCCA
GAGCCATCATTTCTGAAGGAGTGCCGGAGGAGAGGGGACAACCTGTACGTGGTGACAGAGGCTGTTGAAC
TGATCAACAATACTGTGCTGTACGATAGCAGTAGTGTGAATATTTTAGGGAAAATTGCTCTTTGGATTAC
CTATGGCAAGGGTCAAGGCCAAGGAGAGAGTCTCAGAGTGAAGAAGAAGGCGCTGACTCTTCAGAAAGGC
ATGGTGATGGCTTATAAGAGAAAGCAGCTGGTTATCAAGGAGAAAGCCATTCTCATCTCAGATGATGATG
AACAGAGAACCTTTCAAGATGAGTACGAAATTTCCGAAATGGTAGGCTACTGTGCTGCGAGGAGTGAGGG
GTTGCTACCATCATTTCATACCATCTCTCCAACCCTCTTCAATGCCTCATCCAATGATATGAAGTTAAAA
CCAGAGCTATTTCTGACACAGCAATTTTTGAGCGGGCATTTGCCAAAATACGAACAAGTTCACATCCTCC
CAGTAGGAAGAATAGAGGAACCCTTCTGGCAAAATTTCAAGCATCTACAAGAGGAGGTTTTCCAGAAAAT
AAAGACACTGGCTCAGCTCTCAAAGGATGTTCAGGATGTCATGTTCTACAGTATCCTGGCCATGCTCAGA
GACAGAGGGGCTCTACAGGACCTGATGAACATGCTGGAATTGGACAGCTCAGGTCATTTGGATGGCCCTG
GTGGTGCCATCCTAAAGAAACTTCAACAGGATTCAAACCATGCATGGTTTAACCCAAAGGACCCCATTCT
TTATCTCCTTGAAGCCATAATGGTGCTGAGTGACTTCCAACACGATTTGCTGGCCTGTTCCATGGAGAAG
AGGATCCTGCTTCAGCAACAGGAGCTGGTAAGGAGCATCCTGGAGCCAAACTTCAGATACCCCTGGAGCA
TTCCCTTCACCCTCAAACCTGAGCTCCTCGCCCCACTCCAGAGTGAGGGTTTGGCCATCACCTATGGCCT
GCTGGAGGAGTGTGGCCTTAGGACGGAGCTGGATAACCCCAGGTCAACCTGGGATGTAGAAGCAAAGATG
CCCCTGTCTGCCCTCTATGGGACTCTCTCATTGCTGCAGCAGCTGGCTGAGGCC


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
>RC223817 protein sequence
Red=Cloning site Green=Tags(s)

MPSMLERISKNLVKEIGSKDLTSVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSS
SVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDP
EPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKG
MVMAYKRKQLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLK
PELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLR
DRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEK
RILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRTELDNPRSTWDVEAKM
PLSALYGTLSLLQQLAEA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_031415
ORF Size 1524 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_031415.3
RefSeq Size 2731 bp
RefSeq ORF 1527 bp
Locus ID 56169
UniProt ID Q9BYG8
Cytogenetics 8q24.21
Domains DFNA5
MW 57.7 kDa
Gene Summary The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).[UniProtKB/Swiss-Prot Function]

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