FOLR2 (NM_000803) Human Tagged ORF Clone

CAT#: RC212993L1

Lenti ORF clone of Human folate receptor 2 (fetal) (FOLR2), transcript variant 1 , Myc-DDK-tagged

  • LentiORF®

Need custom modification / cloning service?
Get a free quote

USD 598.00


Availability*
In Stock

Size
    • 10 ug

Cited in 2 publications.

Product images

Specifications

Product Data
Product Name FOLR2 (NM_000803) Human Tagged ORF Clone
Symbol FOLR2
Synonyms BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3
Vector pLenti-C-Myc-DDK
Sequence Data
The ORF insert of this clone is exactly the same as(RC212993).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_000803
ORF Size 765 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_000803.2, NP_000794
RefSeq Size 1119
RefSeq ORF 768
Locus ID 2350
Cytogenetics 11q13.4
Domains Folate_rec
Protein Families Secreted Protein, Druggable Genome
MW 29.1 kDa
Gene Summary The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)