GPR126 (ADGRG6) (NM_020455) Human Tagged ORF Clone

CAT#: RC212889

GPR126 (Myc-DDK-tagged)-Human G protein-coupled receptor 126 (GPR126), transcript variant a1

Product Images

Circular map for RC212889

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: GPR126
• Synonyms: APG1; DREG; GPR126; LCCS9; PR126; PS1TP2; STQTL1; VIGR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC212889 representing NM_020455
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGTTTCGCTCAGATCGAATGTGGAGCTGCCATTGGAAATGGAAGCCCAGTCCTCTCCTGTTCTTAT
  TTGCTTTATATATCATGTGTGTTCCTCACTCAGTGTGGGGATGTGCCAACTGCCGAGTGGTTTTGTCCAA
  CCCTTCTGGGACCTTTACTTCTCCATGCTACCCTAACGACTACCCAAACAGCCAGGCTTGCATGTGGACG
  CTCCGAGCCCCCACCGGTTATATCATTCAGATAACATTTAACGACTTTGACATTGAAGAAGCTCCCAATT
  GCATTTATGACTCATTATCCCTTGATAATGGAGAGAGCCAGACTAAATTTTGTGGAGCAACTGCCAAAGG
  CCTATCATTTAACTCAAGTGCGAATGAGATGCATGTGTCCTTTTCAAGTGACTTTAGCATCCAGAAGAAA
  GGTTTCAATGCCAGCTACATCAGAGTTGCCGTGTCCTTAAGGAATCAAAAGGTCATTTTACCCCAGACAT
  CAGATGCTTACCAGGTATCTGTTGCAAAAAGCATCTCTATTCCAGAGCTCAGTGCTTTCACACTCTGCTT
  TGAAGCAACCAAAGTTGGCCATGAAGACAGTGATTGGACAGCTTTCTCCTACTCAAATGCATCCTTCACA
  CAATTGCTCAGTTTTGGAAAGGCCAAGAGTGGCTACTTTCTATCCATTTCTGATTCAAAATGTTTGTTGA
  ATAATGCATTACCTGTCAAAGAAAAAGAAGACATTTTTGCAGAAAGCTTTGAACAGCTCTGCCTTGTTTG
  GAATAATTCTTTGGGCTCTATTGGTGTAAATTTCAAAAGAAACTATGAAACAGTTCCATGTGATTCTACC
  ATTAGTAAAGTTATTCCTGGGAATGGGAAATTGTTGTTGGGCTCCAATCAAAATGAAATTGTCTCTCTAA
  AAGGGGACATTTATAACTTTCGACTTTGGAATTTTACCATGAATGCCAAAATCCTCTCCAACCTCAGCTG
  TAATGTGAAAGGGAATGTAGTCGACTGGCAAAATGACTTCTGGAATATCCCAAACCTAGCTCTGAAAGCT
  GAAAGCAACCTAAGCTGTGGTTCCTACCTGATCCCGCTCCCAGCAGCAGAACTGGCCAGCTGTGCAGACC
  TGGGGACCCTCTGTCAAGCTACTGTAAACTCTCCTAGTACTACACCACCCACTGTCACCACTAACATGCC
  TGTTACTAACAGAATCGATAAACAAAGGAATGATGGAATTATCTATAGAATATCCGTAGTGATTCAGAAC
  ATCCTTCGTCACCCTGAGGTAAAAGTACAGAGCAAGGTGGCAGAATGGCTCAATTCAACCTTCCAAAATT
  GGAACTACACGGTTTATGTCGTTAATATCAGTTTTCACCTGAGTGCTGGAGAGGACAAGATTAAAGTCAA
  GAGAAGCCTTGAGGATGAGCCAAGGTTGGTGCTTTGGGCCCTTCTAGTTTACAATGCTACCAACAATACT
  AATTTAGAAGGAAAAATCATTCAGCAGAAGCTCCTAAAAAATAATGAGTCCTTGGATGAAGGCTTGAGGC
  TACATACAGTGAATGTGAGACAACTGGGTCATTGTCTTGCCATGGAGGAACCCAAAGGCTACTACTGGCC
  ATCTATCCAACCTTCTGAATACGTTCTTCCTTGTCCAGACAAGCCTGGCTTTTCTGCTTCTCGGATATGT
  TTTTACAATGCTACCAACCCATTGGTAACCTACTGGGGACCTGTTGATATCTCCAACTGTTTAAAAGAAG
  CAAATGAAGTTGCTAACCAGATTTTAAATTTAACTGCTGATGGGCAGAACTTAACCTCAGCCAATATTAC
  CAACATTGTGGAACAGGTCAAAAGAATTGTGAATAAAGAAGAAAACATTGATATAACACTTGGCTCAACT
  CTAATGAATATATTTTCTAATATCTTAAGCAGTTCAGACAGTGACTTGCTTGAGTCATCTTCTGAAGCTT
  TAAAAACAATTGATGAATTGGCCTTCAAGATAGACCTAAATAGCACATCACATGTGAATATTACAACTCG
  GAACTTGGCTCTCAGCGTATCATCCCTGTTACCAGGGACAAATGCAATTTCAAATTTTAGCATTGGTCTT
  CCAAGCAATAATGAATCGTATTTCCAGATGGATTTTGAGAGTGGACAAGTGGATCCACTGGCATCTGTAA
  TTTTGCCTCCAAACTTACTTGAGAATTTAAGTCCAGAAGATTCTGTATTAGTTAGAAGAGCACAGTTTAC
  TTTCTTCAACAAAACTGGACTTTTCCAGGATGTAGGACCCCAAAGAAAAACTTTAGTGAGTTATGTGATG
  GCGTGCAGTATTGGAAACATTACTATCCAGAATCTGAAGGATCCTGTTCAAATAAAAATCAAACATACAA
  GAACTCAGGAAGTGCATCATCCCATCTGTGCCTTCTGGGATCTGAACAAAAACAAAAGTTTTGGAGGATG
  GAACACGTCAGGATGTGTTGCACACAGAGATTCAGATGCAAGTGAGACAGTCTGCCTGTGTAACCACTTC
  ACACACTTTGGAGTTCTGATGGACCTTCCAAGAAGTGCCTCACAGTTAGATGCAAGAAACACTAAAGTCC
  TCACTTTCATCAGCTATATTGGGTGTGGAATATCTGCTATTTTTTCAGCAGCAACTCTCCTGACATATGT
  TGCTTTTGAGAAATTGCGAAGGGATTATCCCTCCAAAATCTTGATGAACCTGAGCACAGCCCTGCTGTTC
  CTGAATCTCCTCTTCCTCCTAGATGGCTGGATCACCTCCTTCAATGTGGATGGACTTTGCATTGCTGTTG
  CAGTCCTGTTGCATTTCTTCCTTCTGGCAACCTTTACCTGGATGGGGCTAGAAGCAATTCACATGTACAT
  TGCTCTAGTTAAAGTATTTAACACTTACATTCGCCGATACATTCTAAAATTCTGCATCATTGGCTGGGGT
  TTGCCTGCCTTAGTGGTGTCAGTTGTTCTAGCGAGCAGAAACAACAATGAAGTCTATGGAAAAGAAAGTT
  ATGGGAAAGAAAAAGGTGATGAATTCTGTTGGATTCAAGATCCAGTCATATTTTATGTGACCTGTGCTGG
  GTATTTTGGAGTCATGTTTTTTCTGAACATTGCCATGTTCATTGTGGTAATGGTGCAGATCTGTGGGAGG
  AATGGCAAGAGAAGCAACCGGACCCTGAGAGAAGAAGTGTTAAGGAACCTGCGCAGTGTGGTTAGCTTGA
  CCTTTCTGTTGGGCATGACATGGGGTTTTGCATTCTTTGCCTGGGGACCCTTAAATATCCCCTTCATGTA
  CCTCTTCTCCATCTTCAATTCATTACAAGGCTTATTTATATTCATCTTCCACTGTGCTATGAAGGAGAAT
  GTTCAGAAACAGTGGCGGCGGCATCTCTGCTGTGGTAGATTTCGGTTAGCAGATAACTCAGATTGGAGTA
  AGACAGCTACCAATATCATCAAGAAAAGTTCTGATAATCTAGGAAAATCTTTGTCTTCAAGCTCCATTGG
  TTCCAACTCAACCTATCTTACATCCAAATCTAAATCCAGCTCTACCACCTATTTCAAAAGGAATAGCCAC
  ACAGATAATGTCTCCTATGAGCATTCCTTCAACAAAAGTGGATCACTCAGACAGTGCTTCCATGGACAAG
  TCCTTGTCAAAACTGGCCCATGC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC212889 representing NM_020455
  Red=Cloning site Green=Tags(s)
  
  MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPHSVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWT
  LRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKK
  GFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYSNASFT
  QLLSFGKAKSGYFLSISDSKCLLNNALPVKEKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDST
  ISKVIPGNGKLLLGSNQNEIVSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKA
  ESNLSCGSYLIPLPAAELASCADLGTLCQATVNSPSTTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQN
  ILRHPEVKVQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKVKRSLEDEPRLVLWALLVYNATNNT
  NLEGKIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKGYYWPSIQPSEYVLPCPDKPGFSASRIC
  FYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGST
  LMNIFSNILSSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNAISNFSIGL
  PSNNESYFQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVM
  ACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHF
  THFGVLMDLPRSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLF
  LNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWG
  LPALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGR
  NGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKEN
  VQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSH
  TDNVSYEHSFNKSGSLRQCFHGQVLVKTGPC
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_020455
• ORF Size: 3663 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020455.5, NP_065188.4
• RefSeq Size: 6980 bp
• RefSeq ORF: 3666 bp
• Locus ID: 57211
• UniProt ID: Q86SQ4
• Cytogenetics: 6q24.2
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 137.2 kDa
• Gene Summary: This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]