ACTG2 (NM_001615) Human Tagged ORF Clone
CAT#: RC203151
ACTG2 (Myc-DDK-tagged)-Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1
Specifications
Product Data | |
Product Name | ACTG2 (NM_001615) Human Tagged ORF Clone |
Symbol | ACTG2 |
Synonyms | ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM |
Vector | pCMV6-Entry |
Sequence Data |
>RC203151 representing NM_001615
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTGTGAAGAGGAGACCACCGCGCTCGTGTGTGACAATGGCTCTGGCCTGTGCAAGGCAGGCTTCGCAG GAGATGATGCCCCCCGGGCTGTCTTCCCCTCCATTGTGGGCCGCCCTCGCCACCAGGGTGTGATGGTGGG AATGGGCCAGAAAGACAGCTATGTGGGGGATGAGGCTCAGAGCAAGCGAGGGATCCTAACTCTCAAATAC CCCATTGAACACGGCATCATCACCAACTGGGATGACATGGAGAAGATCTGGCACCACTCCTTCTACAATG AGCTGCGTGTAGCACCTGAAGAGCACCCCACCCTGCTCACAGAGGCTCCCCTAAATCCCAAGGCCAACAG GGAGAAGATGACCCAGATCATGTTTGAAACCTTCAATGTCCCTGCCATGTACGTCGCCATTCAAGCTGTG CTCTCCCTCTATGCCTCTGGCCGCACGACAGGCATCGTCCTGGATTCAGGTGATGGCGTCACCCACAATG TCCCCATCTATGAAGGCTATGCCCTGCCCCATGCCATCATGCGCCTGGACTTGGCTGGCCGTGACCTCAC GGACTACCTCATGAAGATCCTCACAGAGAGAGGCTATTCCTTTGTGACCACAGCTGAGAGAGAAATTGTG CGAGACATCAAGGAGAAGCTGTGCTATGTGGCCCTGGATTTTGAGAATGAGATGGCCACAGCAGCTTCCT CTTCCTCCCTGGAGAAGAGCTATGAGCTGCCAGATGGGCAGGTTATCACCATTGGCAATGAGCGCTTCCG CTGCCCTGAGACCCTCTTCCAGCCTTCCTTTATTGGCATGGAGTCCGCTGGAATTCATGAGACAACCTAC AATTCCATCATGAAGTGTGACATTGACATCCGTAAGGACTTATATGCCAACAATGTCCTCTCTGGGGGCA CCACCATGTACCCTGGCATTGCTGACAGGATGCAGAAGGAGATCACAGCCCTGGCCCCCAGCACCATGAA GATCAAGATTATTGCTCCCCCAGAGCGGAAGTACTCAGTCTGGATCGGGGGCTCTATCCTGGCCTCTCTC TCCACCTTCCAGCAGATGTGGATCAGCAAGCCTGAGTATGATGAGGCAGGGCCCTCCATTGTCCACAGGA AGTGCTTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC203151 representing NM_001615
Red=Cloning site Green=Tags(s) MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKY PIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAV LSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIV RDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTY NSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASL STFQQMWISKPEYDEAGPSIVHRKCF TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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Tag | Myc-DDK |
ACCN | NM_001615 |
ORF Size | 1128 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reference Data | |
RefSeq | NM_001615.1, NM_001615.2, NM_001615.3, NP_001606 |
RefSeq Size | 1345 |
RefSeq ORF | 1131 |
Locus ID | 72 |
Cytogenetics | 2p13.1 |
Domains | ACTIN |
Protein Pathways | Vascular smooth muscle contraction |
MW | 41.7 kDa |
Gene Summary | Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
,Halim, D;Hofstra, RM;Signorile, L;Verdijk, RM;van der Werf, CS;Sribudiani, Y;Brouwer, RW;van IJcken, WF;Dahl, N;Verheij, JB;Baumann, C;Kerner, J;van Bever, Y;Galjart, N;Wijnen, RM;Tibboel, D;Burns, AJ;Muller, F;Brooks, AS;Alves, MM;,
Hum. Mol. Genet. Dec 2015
,PubMed ID 26647307
[ACTG2]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
cDNA Clone Resources |
Other Versions
SKU | Description | Size | Price |
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RC203151L2V | Lenti ORF particles, ACTG2 (mGFP-tagged) - Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1, 200ul, >10^7 TU/mL |
USD 1,110.00 |
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RC203151L4 | Lenti ORF clone of Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1, mGFP tagged |
USD 860.00 |
|
RC203151L4V | Lenti ORF particles, ACTG2 (mGFP-tagged) - Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1, 200ul, >10^7 TU/mL |
USD 1,110.00 |
|
RC203151L3V | Lenti ORF particles, ACTG2 (Myc-DDK tagged) - Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 , 200ul, >10^7 TU/mL |
USD 1,000.00 |
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RC203151L2 | Lenti ORF clone of Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1, mGFP tagged |
USD 860.00 |
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RC203151L1V | Lenti ORF particles, ACTG2 (Myc-DDK tagged) - Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 , 200ul, >10^7 TU/mL |
USD 1,000.00 |
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RC203151L3 | Lenti ORF clone of Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 , Myc-DDK-tagged |
USD 790.00 |
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RC203151L1 | Lenti ORF clone of Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 , Myc-DDK-tagged |
USD 790.00 |
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RG203151 | ACTG2 (GFP-tagged) - Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 |
USD 650.00 |
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SC319705 | ACTG2 (untagged)-Human actin, gamma 2, smooth muscle, enteric (ACTG2), transcript variant 1 |
USD 740.00 |
USD 299.00
USD 550.00