Human DcR1 (TNFRSF10C) ELISA KIT (1 x 96 wells)
CAT#: EA102191
For Quantitative Detection of human TRAILR3 in cell culture supernates, serum and plasma (heparin, EDTA).
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human TNFRSF10C |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 62.5pg/ml-4000pg/ml |
Specificity | This kit is used for quantitative detection of Human TNFRSF10C |
Sensitivity | <12pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | TRAILR3/TNFRSF10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. TRAILR3 gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. |
Gene Symbol | TNFRSF10C |
Gene ID | 8794 |
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