PCNA Mouse Monoclonal Antibody [Clone ID: OTI2G7]

CAT#: TA800875

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Mouse monoclonal anti-PCNA antibody, clone 2G7, Loading, clone OTI2G7 (formerly 2G7)



  View other "OTI2G7" antibodies (5)

USD 447.00


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Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI2G7
Applications IF, WB
Recommended Dilution WB 1:2000, IF 1:50
Reactivities Human, Monkey, Mouse, Rat, Dog
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PCNA (NP_002583) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 28.6 kDa
Gene Name proliferating cell nuclear antigen
Background The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Synonyms ATLD2
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

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